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Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Departing from
Italy
Cruise Specials

Costa Cruise Lines, Costa Smeralda
Costa Smeralda Cruises7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia, Savona, Marseille, Barcelona, La Goulette, Palermo, Civitavecchia
2026 Sails: Jan 23, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises5 Night - Western Mediterranean from Palermo
Starting in Palermo, Civitavecchia, Savona, Marseille, Barcelona, Marseille
2026 Sails: Jan 23, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises3 Night - Western Mediterranean from Palermo
Starting in Palermo, Civitavecchia, Savona, Marseille
2026 Sails: Jan 23, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda Cruises7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, La Goulette, Palermo, Civitavecchia, Savona
2026 Sails: Jan 24, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises4 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia, Savona, Marseille, Barcelona, Marseille
2026 Sails: Jan 24, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises2 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia, Savona, Marseille
2026 Sails: Jan 24, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises3 Night - Western Mediterranean from Rome (Civitavecchia) to Barcelona
Starting in Civitavecchia, Savona, Marseille, Barcelona
2026 Sails: Jan 24, More...
Costa Cruise Lines, Costa Toscana
Costa Toscana Cruises3 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Marseille
2026 Sails: Jan 25, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda Cruises4 Night - Cruise from Palermo to Barcelona
Starting in Palermo, Civitavecchia, Savona, Marseille, Barcelona
2026 Sails: Jan 29, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda Cruises7 Night - Western Mediterranean from Palermo
Starting in Palermo (Sicily), Civitavecchia / Rome, Italy, Savona, Italy, Marseille, France, Barcelona, Spain, Balearic sea darkest spot, La Goulette, Tunisia, Tunis Gulf, Palermo (Sicily)
2026 Sails: Jan 29, Feb 5, Feb 12, Feb 19, Feb 26, Mar 5, More...

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Italy Cruise Departures