Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Virgin Voyages, Scarlet Lady

9 Night - Italy & French Riviera
Starting in Civitavecchia (Rome), Italy, Catania, Sicily, Italy, Naples, Italy, Ajaccio, Corsica, France, Cannes, France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 22, More...

Costa Cruise Lines, Costa Fascinosa

7 Night - Eastern Mediterranean from Taranto
Starting in Taranto, Argostoli (Cephalonia), Mykonos, Piraeus (Athens), Malta / La Valletta, Catania, Taranto
2026 Sails: Aug 23, Sep 6, More...

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Savona
Starting in Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia (costa Smeralda), Civitavecchia (Rome), Savona
2026 Sails: Aug 23, Aug 30, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy
2026 Sails: Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, 2027: May 2, May 9, May 16, May 23, Jun 6, Jun 13, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 8, Aug 22, Aug 29, More...

MSC Cruises, MSC Musica

7 Night - Mediterranean
Starting in Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy
2026 Sails: Aug 23, Aug 30, More...

MSC Cruises, MSC Seaview

7 Night - Mediterranean
Starting in Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, More...

MSC Cruises, MSC World Europa

7 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Eastern Mediterranean
Starting in Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Venice (Trieste), Italy, Venice (Ravenna), Italy
2026 Sails: Aug 23, Sep 6, More...

Norwegian Cruise Line, Norwegian Pearl

7 Night - Europe - Greek Isles - Venice
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Olympia / Katakolon, Greece, Mykonos, Greece, Santorini Island, Greece, Piraeus / Athens, Greece
2026 Sails: Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, More...

Royal Caribbean, Odyssey of the Seas

7 Night - Greek Isles Cruise
Starting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 23, Aug 30, Sep 6, Sep 13, Oct 4, More...

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