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Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Departing from
Italy
Cruise Specials

Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa4 Night - Western Mediterranean from Savona
Starting in Savona, Barcelona, Marseille, Savona
2026 Sails: Oct 4, Oct 8, Oct 15, Oct 25, Nov 1, More...
Costa Cruise Lines, Costa Fascinosa
Costa Fascinosa3 Night - Western Mediterranean from Savona
Starting in Savona, Barcelona, Marseille
2026 Sails: Oct 4, Nov 1, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, La Goulette (Tunis), Palermo, Civitavecchia (Rome), Savona
2026 Sails: Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 15, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica5 Night - Western Mediterranean from Savona to Palermo
Starting in Savona, Marseille, Barcelona, La Goulette (Tunis), Palermo
2026 Sails: Oct 4, More...
MSC Cruises, MSC Armonia
MSC Armonia7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy
2026 Sails: Oct 4, Oct 11, Oct 18, Oct 25, 2027: May 2, May 9, May 16, May 23, Jun 6, Jun 13, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 8, Aug 22, Aug 29, Sep 19, Oct 3, 2028: Apr 2, Apr 9, Apr 16, Apr 23, More...
MSC Cruises, MSC Seaview
MSC Seaview7 Night - Mediterranean
Starting in Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy
2026 Sails: Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, More...
MSC Cruises, MSC World Europa
MSC World Europa7 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Oct 4, Nov 1, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem7 Night - Eastern Mediterranean
Starting in Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Corfu, Greece, Kotor, Montenegro, Zadar, Croatia, Venice (Trieste), Italy, Venice (Ravenna), Italy
2026 Sails: Oct 4, Oct 18, More...
Norwegian Cruise Line, Norwegian Pearl
Norwegian Pearl7 Night - Europe - Greek Isles - Venice
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Olympia / Katakolon, Greece, Mykonos, Greece, Santorini Island, Greece, Piraeus / Athens, Greece
2026 Sails: Oct 4, Oct 18, More...

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Italy Cruise Departures