Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Lecce : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Costa Cruise Lines, Costa Deliziosa

14 Night - Eastern Mediterranean from Marghera
Starting in Marghera, Bari, Corfu, Argostoli / Cephalonia, Dubrovnik, Croatia, Kotor, Montenegro, Zadar, Marghera, Bari, Santorini, Mykonos, Katakolon, Marghera
2026 Sails: Aug 22, More...

Virgin Voyages, Scarlet Lady

9 Night - Italy & French Riviera
Starting in Civitavecchia (Rome), Italy, Catania, Sicily, Italy, Naples, Italy, Ajaccio, Corsica, France, Cannes, France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 22, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy
2026 Sails: Aug 23, More...

Uniworld Tours, S.S. La Venezia Tours

16 Night - Cruise & Rail : Venice, Istanbul & the Balkans
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Pula, Rijeka, Sarajevo, Mostar, Belgrade, Sofia, Plovdiv, Istanbul
2026 Sails: Aug 23, Sep 27, 2027: May 2, More...

Cunard Line, Queen Victoria

14 Night - Italy, Spain and Adriatic
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Palma De Mallorca, Spain, Barcelona, Spain
2026 Sails: Aug 24, More...

Cunard Line, Queen Victoria

21 Night - Italy, France, Spain and Adriatic
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Palma De Mallorca, Spain, Barcelona, Spain, Ibiza, Spain, Ajaccio, Corsica, France, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 24, More...

Celebrity Cruises, Celebrity Equinox

9 Night - Italian Riviera & France
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: Aug 25, More...

Norwegian Line Tours, Norwegian Viva Tours

13 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Dubrovnik, Croatia, Montenegro, Piraeus / Athens, Greece, Santorini Island, Greece, Rhodes, Greece, Kusadasi, Turkey, Thessaloniki, Greece, Istanbul, Turkey
2026 Sails: Aug 25, More...

Windstar, Wind Surf

15 Night - Star Collector : Iconic Italy and Croatia
Starting in Rome, Bastia, Cannes, Monte Carlo, Genoa, Italy, Portofino, Porto Ercole, Rome, Sorrento, Giardini Naxos, Kotor, Dubrovnik, Croatia, Split, Rovinj, Venice
2026 Sails: Aug 26, More...

Windstar, Wind Surf

7 Night - Jewels of the Italian and French Rivieras
Starting in Rome, Bastia, Cannes, Monte Carlo, Genoa, Italy, Portofino, Porto Ercole, Rome
2026 Sails: Aug 26, More...

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