Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Celebrity Cruises, Celebrity Constellation

10 Night - Best of Italy & Croatia Cruise
Starting in Ravenna, Italy, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Sicily (Messina), Italy, Amalfi Coast (Salerno), Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jun 19, Jul 10, Jul 31, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy
2026 Sails: Jun 19, More...

Norwegian Line Tours, Norwegian Epic Tours

9 Night - Rome & Etruria Pre Cruisetour
Starting in At Hotel, Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Livorno / Florence / Pisa, Italy, Nice / Monaco (Villefranche), France, Provence, Marseille, France, Barcelona, Spain
2026 Sails: Jun 19, Jul 17, Jul 31, Sep 11, More...

Atlas Ocean Voyages, World Traveller

11 Night - Venice to Rome
Starting in Venice, Italy, Piran, Rovinj, Hvar Island, Dubrovnik (Old Town), Otranto (Puglia), Taormina (Mount Etna), Italy, Lipari (Aeolian Islands), Italy, Amalfi (Ravello), Italy, Capri, Ponza, Civitavecchia (Rome)
2026 Sails: Jun 20, More...

Costa Cruise Lines, Costa Deliziosa

14 Night - Eastern Mediterranean from Marghera
Starting in Marghera, Bari, Corfu, Zakynthos, Argostoli / Cephalonia, Dubrovnik, Croatia, Split, Croatia, Marghera, Bari, Santorini, Mykonos, Argostoli / Cephalonia, Marghera
2026 Sails: Jun 20, Sep 12, More...

Royal Caribbean, Explorer of the Seas

7 Night - Greece & Adriatic Cruise
Starting in Ravenna, Italy, Bay of Kotor (Cruising), Kotor, Montenegro, Athens (Piraeus), Greece, Santorini, Greece, Zadar, Croatia, Ravenna, Italy
2026 Sails: Jun 20, Jul 18, Sep 12, More...

MSC Cruises, MSC World Europa

3 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta
2026 Sails: Jun 21, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Europe - Adriatic & Greece - Venice
Starting in Venice (Ravenna), Italy, Split, Croatia, Kotor, Montenegro, Dubrovnik, Croatia, Corfu, Greece, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Jun 21, More...

PONANT, Le Dumont-d'Urville

10 Night - 5Th Opera Festival at Sea
Starting in Venice, Ravenna, Ancona, Otranto, Taormina, Sicily, Amalfi, Porto Santo Stefano, Livorno, Portofino, Nice
2026 Sails: Jun 22, More...

Princess Cruises, Enchanted Princess

14 Night - Mediterranean, Aegean & Adriatic
Starting in Civitavecchia (for Rome), Italy, Katakolon (for Olympia), Greece, Santorini, Greece, Kusadasi, Turkey (for Ephesus), Amalfi Coast (Salerno), Civitavecchia (for Rome), Italy, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2026 Sails: Jun 23, More...

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