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Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Departing from
Italy
Cruise Specials

Explora Journeys, EXPLORA II
EXPLORA II19 Night - An Extended Journey of Shifting Cultures & Coastal Continuity
Starting in Civitavecchia (Rome), Amalfi, Sardinia / Cagliari, Cartagena ES, Malaga, Spain, Tangier, Alicante, Barcelona, Valencia, Palma De Mallorca, Palamos, Marseille, Genoa, Villefranche-Sur-Mer (Nice), Livorno (Florence), Civitavecchia (Rome)
2027 Sails: Jan 14, More...
Explora Journeys, EXPLORA II
EXPLORA II10 Night - A Journey from Amalfi's Cliffs to Andalusian Sun
Starting in Civitavecchia (Rome), Amalfi, Sardinia / Cagliari, Cartagena ES, Malaga, Spain, Tangier, Alicante, Barcelona
2027 Sails: Jan 14, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia2 Night - Mediterranean
Starting in Civitavecchia (Rome), Italy, Valencia, Spain
2027 Sails: Jan 14, More...
MSC Cruises, MSC Lirica
MSC Lirica7 Night - Mediterranean
Starting in Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey, Corfu, Greece, Bari, Italy
2027 Sails: Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, More...
Viking Ocean, Viking Saturn
Viking Saturn7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Jan 17, Mar 28, More...
Viking Ocean, Viking Star
Viking Star14 Night - Cities of Antiquity
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Valletta, Sail the Ionian Sea, Corfu (Kerkyra), Katakolon (Olympia), Kalamata, Crete (Heraklion), Rhodes, Santorini (Thira), Athens (Piraeus)
2027 Sails: Jan 19, More...
Costa Cruise Lines, Costa Pacifica
Costa Pacifica11 Night - Mediterranean Roundtrip from Savona
Starting in Savona, Naples, Palermo, La Goulette (Tunis), Tangier, Malaga, Valencia, Barcelona, Marseille, Savona
2027 Sails: Jan 22, More...
Windstar, Star Explorer
Star Explorer8 Night - Winter Italy and the Dalmatian Coast
Starting in Civitavecchia, Rome, Naples, Messina, Taormina, Dubrovnik, Croatia, Zadar, Venice
2027 Sails: Jan 22, Mar 27, Dec 12, 2028: Jan 29, Mar 17, Oct 29, More...
Viking Ocean, Viking Mira
Viking Mira7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2027 Sails: Jan 27, Nov 24, 2028: Jan 19, Mar 23, More...
Windstar, Star Explorer
Star Explorer8 Night - Winter Italy and the Dalmatian Coast
Starting in Venice, Zadar, Dubrovnik, Croatia, Messina, Taormina, Naples, Civitavecchia, Rome
2027 Sails: Jan 30, Mar 19, Dec 20, 2028: Feb 22, Mar 25, Nov 6, More...

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Italy Cruise Departures