Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome)
2026 Sails: Oct 2, More...

Norwegian Line Tours, Norwegian Viva Tours

12 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Dubrovnik, Croatia, Montenegro, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy, La Spezia, Italy, Nice / Monaco (Villefranche), France, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Oct 2, More...

Costa Cruise Lines, Costa Deliziosa

7 Night - Eastern Mediterranean from Trieste
Starting in Trieste, Bari, Corfu, Siracusa, Malta / La Valletta, Split, Trieste
2026 Sails: Oct 3, Oct 17, Oct 31, More...

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, La Goulette (Tunis), Palermo, Civitavecchia (Rome)
2026 Sails: Oct 3, Oct 10, Oct 17, Oct 24, Oct 31, Nov 14, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Oct 3, More...

Oceania Cruises, Oceania Allura

7 Night - Mediterranean Melange
Starting in Trieste, Ravenna, Rijeka, Split, Brindisi, Corfu, Gythion, Athens (Piraeus)
2026 Sails: Oct 3, More...

Viking Ocean, Viking Neptune

Deal link -> Special

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Oct 3, More...

Costa Cruise Lines, Costa Fascinosa

4 Night - Western Mediterranean from Savona
Starting in Savona, Barcelona, Marseille, Savona
2026 Sails: Oct 4, Oct 8, Oct 15, Oct 25, Nov 1, More...

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, La Goulette (Tunis), Palermo, Civitavecchia (Rome), Savona
2026 Sails: Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, Nov 15, More...

Ritz-Carlton, Ilma

9 Night - Venice / Rome (Civitavecchia)
Starting in Venice, Trieste, Piran, Zadar, Hvar, Dubrovnik, Croatia, Kotor, Sorrento, Rome (Civitavecchia)
2026 Sails: Oct 4, More...

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