Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Viking Ocean, Viking Neptune

14 Night - Mediterranean & Adriatic Odyssey
Starting in Rome (Civitavecchia), Naples, Sicily (Syracuse IT), Sail the Mediterranean Sea, Bari, Split, Zadar, Venice (Fusina), Ancona, Dubrovnik, Croatia, Corfu (Kerkyra), Kalamata, Crete (Souda Bay), Athens (Piraeus)
2027 Sails: Jan 5, More...

Viking Ocean, Viking Star

7 Night - Amalfi Coast, Africa & Iberia
Starting in Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2027 Sails: Jan 5, Feb 16, Mar 2, Mar 16, Nov 13, Dec 12, 2028: Mar 16, More...

Viking Ocean, Viking Vesta

14 Night - Ancient Mediterranean Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2027 Sails: Jan 6, More...

Viking Ocean, Viking Vesta

7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2027 Sails: Jan 6, Nov 23, More...

MSC Cruises, MSC Lirica

7 Night - Mediterranean
Starting in Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey, Corfu, Greece, Bari, Italy
2027 Sails: Jan 9, More...

MSC Cruises, MSC Lirica

4 Night - Mediterranean
Starting in Bari, Italy, Piraeus (Athens), Greece, Izmir (Ephesus), Turkey, Istanbul, Turkey
2027 Sails: Jan 9, More...

MSC Cruises, MSC Lirica

2 Night - Mediterranean
Starting in Bari, Italy, Piraeus (Athens), Greece
2027 Sails: Jan 9, More...

Costa Cruise Lines, Costa Pacifica

12 Night - Mediterranean Roundtrip from Savona
Starting in Savona, Naples, Palermo, La Goulette (Tunis), Tangier, Malaga, Alicante, Valencia, Barcelona, Marseille, Savona
2027 Sails: Jan 10, Feb 2, Mar 28, More...

MSC Cruises, MSC Sinfonia

4 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Valencia, Spain
2027 Sails: Jan 12, More...

Explora Journeys, EXPLORA II

Deal link -> Special

6 Night - A Journey Through Cliffs, Islands and Andalusian Light
Starting in Civitavecchia (Rome), Amalfi, Sardinia / Cagliari, Cartagena ES, Malaga, Spain
2027 Sails: Jan 14, More...

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