Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Lecce : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Norwegian Line Tours, Norwegian Viva Tours

12 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy, Livorno / Florence / Pisa, Italy, Nice / Monaco (Villefranche), France, Provence, Marseille, France, Barcelona, Spain
2026 Sails: Jun 12, More...

Costa Cruise Lines, Costa Deliziosa

7 Night - Eastern Mediterranean from Marghera
Starting in Marghera, Bari, Corfu, Argostoli / Cephalonia, Dubrovnik, Croatia, Kotor, Montenegro, Zadar, Croatia, Marghera
2026 Sails: Jun 13, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Ibiza, Barcelona, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Jun 13, More...

Emerald Cruises, Emerald Kaia

7 Night - Adriatic Discovery : Venice, Istria & the Croatian Archipelago
Starting in Venice, Italy, Piran, Slovenia, Mali Losinj, Croatia, Senj, Croatia / Baska, Krk Island, Croatia, Opatija, Croatia, Rovinj, Croatia, Venice, Italy
2026 Sails: Jun 13, Jul 4, Jul 25, 2027: Jun 5, More...

Oceania Cruises, Oceania Allura

12 Night - Adriatic to the Balearics
Starting in Trieste, Split, Kotor, Corfu, Messina (Sicily), Valletta, Tunis (La Goulette), Cartagena ES, Ibiza, Palma De Mallorca, Barcelona
2026 Sails: Jun 13, More...

SeaDream Yacht Club, SeaDream I

7 Night - Dalmatian Coast Discovery Cruise
Starting in Venice, Piran, Rovinj, Opatija, Zadar, Primosten, Dubrovnik, Croatia
2026 Sails: Jun 13, More...

Holland America, Oosterdam

14 Night - Rivieras, Malta & Greek Isles
Starting in Civitavecchia (Rome), Italy, Livorno (Florence / Pisa), Italy, Portofino, Italy, Marseille (Provence), France, Gibraltar, Barcelona, Spain, Valletta, Malta, Souda (Chania), Greece, Thira (Santorini), Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece
2026 Sails: Jun 14, 2027: Jun 19, More...

Holland America, Oosterdam

7 Night - Western Mediterranean
Starting in Civitavecchia (Rome), Italy, Livorno (Florence / Pisa), Italy, Portofino, Italy, Marseille (Provence), France, Gibraltar, Barcelona, Spain
2026 Sails: Jun 14, Jul 26, 2027: Jun 19, More...

Holland America, Oosterdam

21 Night - Ultimate Mediterranean Marvels Collectors' Voyage
Starting in Civitavecchia (Rome), Italy, Livorno (Florence / Pisa), Italy, Portofino, Italy, Marseille (Provence), France, Gibraltar, Barcelona, Spain, Valletta, Malta, Souda (Chania), Greece, Thira (Santorini), Greece, Kusadasi (Ephesus), Turkey, Piraeus (Athens), Greece, Thira (Santorini), Greece, Souda (Chania), Greece, Kusadasi (Ephesus), Turkey, Rhodes, Greece, Mykonos, Greece, Piraeus (Athens), Greece
2026 Sails: Jun 14, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Eastern Mediterranean
Starting in Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Koper, Slovenia, Venice (Ravenna), Italy
2026 Sails: Jun 14, More...

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