Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Costa Cruise Lines, Costa Pacifica

3 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Valencia, Palma De Mallorca
2026 Sails: Apr 4, More...

Costa Cruise Lines, Costa Pacifica

8 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Valencia, Palma De Mallorca, Ibiza, La Spezia, Civitavecchia, Savona
2026 Sails: Apr 4, More...

MSC Cruises, MSC Lirica

7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Kotor, Montenegro, Mykonos, Greece, Syros, Greece, Ancona (Urbino), Italy, Venice / Marghera, Italy
2026 Sails: Apr 4, Apr 11, Apr 18, Apr 25, May 2, May 9, May 16, May 23, May 30, Jun 6, Jun 13, Jun 20, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, More...

MSC Cruises, MSC Sinfonia

7 Night - Mediterranean
Starting in Bari, Italy, Santorini, Greece, Piraeus (Athens), Greece, Katakolon (Olympia), Greece, Cefalonia / Argostoli, Greece, Corfu, Greece, Bari, Italy
2026 Sails: Apr 4, May 2, May 9, May 16, May 23, Jun 27, Jul 4, Jul 18, Jul 25, Aug 1, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, More...

MSC Cruises, MSC Sinfonia

3 Night - Mediterranean
Starting in Bari, Italy, Santorini, Greece, Piraeus (Athens), Greece
2026 Sails: Apr 4, More...

Viking Ocean, Viking Saturn

14 Night - Ancient Adriatic Treasures
Starting in Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 4, More...

Viking Ocean, Viking Saturn

7 Night - Venice, the Adriatic & Greece
Starting in Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Apr 4, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy
2026 Sails: Apr 5, Apr 12, Apr 19, May 24, Jun 14, Jun 21, Jun 28, Jul 12, Jul 19, Aug 30, Sep 6, Sep 13, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, 2027: May 2, May 16, May 23, Jun 6, Jun 20, Jun 27, Jul 4, More...

Princess Cruise Tours, Sun Princess Cruise Tours

20 Night - Classic Italy - Tour 4B
Starting in Venice, Italy, Florence, Italy, Rome, Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain
2026 Sails: Apr 5, Apr 26, Jun 28, Jul 19, Aug 9, Aug 30, More...

Princess Cruise Tours, Sun Princess Cruise Tours

13 Night - Classic Italy - Tour 4A
Starting in Venice, Italy, Florence, Italy, Rome, Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Apr 5, Apr 26, Jun 28, Jul 19, Aug 9, Aug 30, More...

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