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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Balboa : Barro Colorado Island : Bocas del Toro : Cayos Limones : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Windstar, Star Pride
Star Pride21 Night - Star Collector : Costa Rica, Panama & Aruba
Starting in Puerto Caldera, Playa Flamingo, Punta Leona, Costa Rica, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad, Willemstad AN, Kralendijk, Gustavia, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, San Juan
2028 Sails: Feb 21, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra7 Night - Coastal Adventures : Costa Rica & Panama
Starting in Puerto Caldera, Costa Rica, Curu and Isla Tortuga, Costa Rica, Quepos, Costa Rica, Golfito, Costa Rica, Isla Cebaco, Panama, Playa del Muerto / Darien National Park, Panama, Pearl Islands, Panama, Panama City, Panama
2028 Sails: Feb 22, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra18 Night - Discover the Secrets of Panama and Costa Rica
Starting in Puerto Caldera, Costa Rica, Curu and Isla Tortuga, Costa Rica, Quepos, Costa Rica, Golfito, Costa Rica, Isla Cebaco, Panama, Playa del Muerto / Darien National Park, Panama, Pearl Islands, Panama, Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 22, More...
MSC Cruises, MSC Poesia
MSC Poesia21 Night - Caribbean and Antilles
Starting in Miami, Florida, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2028 Sails: Feb 24, More...
Windstar, Star Pride
Star Pride7 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad
2028 Sails: Feb 28, More...
Windstar, Star Pride
Star Pride14 Night - Star Collector : Panama, Aruba & the British Virgin Islands
Starting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad, Willemstad AN, Kralendijk, Gustavia, Jost Van Dyke, Great Harbour, Virgin Gorda / Prickly Pear, British Virgin Islands, San Juan
2028 Sails: Feb 28, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity10 Night - The Americas & Caribbean
Starting in Cartagena CO, Colon, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Fort Lauderdale
2028 Sails: Feb 29, More...
Emerald Cruises, Emerald Azzurra
Emerald Azzurra11 Night - Panama Canal Transit, Colombia & the Grenadines
Starting in Panama City, Panama, Transit Panama Canal / at Sea, San Blas Islands, Panama, Cartagena CO, Santa Marta, Colombia, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Mayreau Island, Saint Vincent and the Grenadines, Bequia Island, Saint Vincent and the Grenadines, Bridgetown, Barbados
2028 Sails: Feb 29, More...
Regent Seven Seas, Seven Seas Prestige
Seven Seas Prestige12 Night - Flavors of Cartagena
Starting in Miami, Key West, Cruising the Florida Straits, George Town, Falmouth, Cruising the Caribbean Sea, Cabo Rojo, Cruising the Caribbean Sea, Cartagena CO, Cruising the Caribbean Sea, Puerto Limon, Panama Canal Daylight Transit, Panama City
2028 Sails: Mar 2, More...
MSC Cruises, MSC Poesia
MSC Poesia21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colombia, Colon, Panama, Puerto Limon, Costa Rica, Roatan Island, Honduras, Belize City, Belize, Miami, Florida, Oranjestad, Aruba, Willemstad AN, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Florida
2028 Sails: Mar 5, More...

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Panama Cruises