Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Disney Cruise Line, Disney Magic

14 Night - Westbound Panama Canal Cruise from Galveston Ending in San Diego
Starting in Galveston, Cartagena ES, Colon, Panama Canal, Cabo San Lucas, Ensenada, San Diego
2028 Sails: Mar 26, More...

Holland America, Oosterdam

12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2028 Sails: Mar 26, More...

Celebrity Cruises, Celebrity Ascent

11 Night - Panama Canal & Southern Caribbean
Starting in Fort Lauderdale, Florida, Puerto Plata, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Curacao, Panama Canal (Cruising), Colon, Panama, George Town, Grand Cayman, Fort Lauderdale, Florida
2028 Sails: Mar 27, More...

Holland America, Eurodam

22 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Acapulco, Guerrero, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Santa Barbara, California, Astoria, Oregon, Victoria CA, Canada, Vancouver, BC, CA
2028 Sails: Apr 1, More...

Holland America, Eurodam

16 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Acapulco, Guerrero, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2028 Sails: Apr 1, More...

Royal Caribbean, Grandeur of the Seas

7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2028 Sails: Apr 2, More...

MSC Cruises, MSC Poesia

18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, San Francisco, California, Seattle, Washington
2028 Sails: Apr 6, More...

Holland America, Oosterdam

21 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Seattle, Washington, Victoria CA, Canada, Vancouver, BC, CA
2028 Sails: Apr 7, More...

Holland America, Oosterdam

15 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2028 Sails: Apr 7, More...

Princess Cruises, Star Princess

16 Night - Panama Canal - Ocean to Ocean
Starting in Port Canaveral (Orlando), Florida, Grand Turk, Turks and Caicos, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2028 Sails: Apr 7, More...

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