Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

MSC Cruises, MSC Poesia

11 Night - Caribbean and Antilles
Starting in Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2028 Sails: Jan 23, More...

Emerald Cruises, Emerald Azzurra

7 Night - Coastal Adventures : Panama & Costa Rica
Starting in Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Jan 24, More...

Norwegian Cruise Line, Norwegian Encore

15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2028 Sails: Jan 24, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Oranjestad, Aruba, Kralendijk, Bonaire, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2028 Sails: Feb 3, More...

Emerald Cruises, Emerald Azzurra

12 Night - Costa Rica, Panama from the Pacific to the Atlantic via the Panama Canal
Starting in San Jose, Costa Rica, San Jose, Costa Rica / Puerto Limon, Costa Rica, Puerto Limon, Costa Rica, Bocas Del Toro, Panama, Transit Panama Canal / Panama City, Panama, Panama City, Panama, Pearl Islands, Panama, Playa del Muerto / Darien National Park, Panama, Isla Cebaco, Panama, Golfito, Costa Rica, Quepos, Costa Rica, Curu and Isla Tortuga / Puerto Caldera, Costa Rica, Puerto Caldera, Costa Rica
2028 Sails: Feb 10, More...

Crystal Cruises, Crystal Serenity

27 Night - The Americas & Caribbean
Starting in Fort Lauderdale, Road Town, Gustavia, St Barthelemy, Roseau, St Kitts (Basseterre), San Juan, St Johns, Pointe-a-Pitre, French West Indies, Castries, St Lucia, St Georges, Kralendijk, Willemstad AN, Oranjestad, Aruba, Cartagena CO, Colon, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Fort Lauderdale
2028 Sails: Feb 12, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida
2028 Sails: Feb 13, More...

Celebrity Cruises, Celebrity Ascent

11 Night - Panama Canal & Southern Caribbean
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Willemstad AN, Curacao, Panama Canal (Cruising), Colon, Panama, George Town, Grand Cayman, Fort Lauderdale, Florida
2028 Sails: Feb 14, More...

Virgin Voyages, Brilliant Lady

16 Night - Panama Canal : Miami to Los Angeles
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Panama, Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Cabo San Lucas, Mexico, Los Angeles, California
2028 Sails: Feb 21, More...

Windstar, Star Pride

14 Night - Star Collector : Latin America Explorer
Starting in Puerto Caldera, Playa Flamingo, Punta Leona, Costa Rica, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad
2028 Sails: Feb 21, More...

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