Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

AmaWaterways Tours, AmaMelodia Tours

10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Palenque, Calamar, Mompox, Magangue, San Felipe, Barranquilla, Panama City
2027 Sails: Jan 13, Mar 10, Apr 21, May 5, May 19, Jun 2, Jun 16, More...

Lindblad Expeditions Tours, National Geographic Quest Tours

8 Night - Exploring Arenal Volcano, Pearl Islands and the Panama Canal
Starting in San Jose, Costa Rica / Arenal Volcano Area, Arenal Volcano Area, San Jose / Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2027 Sails: Jan 13, Jan 21, Nov 22, 2028: Jan 21, More...

Norwegian Cruise Line, Norwegian Sun

12 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Falmouth, Jamaica, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2027 Sails: Jan 13, Feb 17, More...

Princess Cruises, Island Princess

16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Jan 13, More...

Azamara Cruises, Azamara Journey

74 Night - Circle South America Grand Voyage
Starting in Miami, Florida, St John VI, US Virgin Islands, Charlotte Amalie, St Thomas, Philipsburg, Charlestown, Nevis, St Johns AG, Saint-Pierre, Port Elizabeth VC, Bequia, Saint Georges, Grenada, Bridgetown, Scarborough, Tobago, Isle Royale, French Guiana, Belem, Recife, Salvador De Bahia, Buzios, Brazil, Rio De Janeiro, Paraty, Ilhabela, Brazil, Santos (Sao Paulo), Montevideo, Buenos Aires, Montevideo, Punta Del Este, Port Stanley, Falkland Islands, Sailing the Antarctic Peninsula, Ushuaia, Sailing in the Beagle Channel, Ushuaia, Punta Arenas, Sailing in the Chilean Fjords, Puerto Chacabuco, Puerto Montt, San Antonio Cl, Coquimbo, Iquique, Arica, Pisco, Callao (Lima), Panama City (Fuerte Amador), Panama Canal (Cruising), Puerto Limon, Isla San Andres, Cozumel, Mexico, Miami, Florida
2027 Sails: Jan 14, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Willemstad AN, Oranjestad, Aruba, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Miami, Florida, Montego Bay, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2027 Sails: Jan 14, More...

Oceania Cruises, Oceania Marina

10 Night - Panama to Caribbean Joy
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Ocho Rios, Jamaica, George Town, Miami
2027 Sails: Jan 15, More...

PONANT, Le Laperouse

7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Portobelo, Crossing the Panama Canal, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Jan 15, More...

AmaWaterways Tours, AmaMagdalena Tours

10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Palenque, Calamar, Mompox, Magangue, San Felipe, Barranquilla, Panama City
2027 Sails: Jan 16, Mar 13, Mar 27, Apr 10, Apr 24, May 8, More...

Carnival Cruise Lines, Carnival Legend

8 Night - Caribbean & Panama
Starting in Tampa, Fl, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Cayman, Cayman Islands, Tampa, Fl
2027 Sails: Jan 16, Mar 13, More...

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