United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Royal Caribbean, Vision of the Seas

9 Night - Bahamas & Perfect Day Cruise
Starting in Baltimore, Maryland, Orlando (Port Canaveral), Fl, Miami, Florida, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Grand Bahama Island, Bahamas, Baltimore, Maryland
2026 Sails: May 14, More...

Silversea, Silver Moon

7 Night - Seward (Anchorage to Vancouver)
Starting in Seward (Anchorage, Alaska), Cruise Hubbard Glacier, Alaska, Juneau, Alaska, Skagway, Alaska, Sitka, Alaska, Ketchikan, Alaska, Cruise British Columbia Inside Passage, Vancouver
2026 Sails: May 14, More...

Celebrity Cruises, Celebrity Reflection

3 Night - Bahamas & Perfect Day Cruise
Starting in Fort Lauderdale, Florida, Perfect Day Cococay, Bahamas, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: May 15, More...

Celebrity Cruises, Celebrity Summit

7 Night - Alaska Southbound Glacier
Starting in Seward, Alaska, Hubbard Glacier (Cruising), Juneau, Alaska, Skagway, Alaska, Icy Strait Point, Alaska, Ketchikan, Alaska, Inside Passage (Cruising), Vancouver, British Columbia
2026 Sails: May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...

Holland America Tours, Westerdam Tours

9 Night - Classic Denali D8l - Tour D8l
Starting in Fairbanks, Denali National Park, Whittier, Alaska, Cruising Hubbard Glacier, Glacier Bay, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Scenic Cruising the Inside Passage, Vancouver, BC, CA
2026 Sails: May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, More...

Princess Tours, Grand Princess Tours

15 Night - Connoisseur Escorted - Tour Ub8
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 15, Jul 24, More...

Princess Tours, Grand Princess Tours

15 Night - Off the Beaten Path - Tour Qb8
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 15, More...

Princess Tours, Island Princess Tours

12 Night - Off the Beaten Path - Tour Lb5
Starting in Fairbanks, Denali Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 15, Jun 12, Jun 26, Jul 10, Aug 7, More...

Princess Tours, Island Princess Tours

12 Night - Denali Explorer - Tour Hb5
Starting in Anchorage, Mount Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 15, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...

Princess Tours, Island Princess Tours

12 Night - Connoisseur Escorted - Tour Rb5
Starting in Anchorage, Mount Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 15, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...

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United States Cruise Departures