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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

American Cruise Lines, American Symphony
American Symphony8 Night - Tennessee Rivers Cruise
Starting in Chattanooga, TN, Cruising the Tennessee River, Decatur, AL, Florence, AL, Savannah, TN, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Nashville, TN
2026 Sails: May 5, May 19, Jun 2, Jun 16, Jul 28, Sep 22, Oct 6, Oct 20, 2027: May 4, May 18, Jun 1, Jun 15, Oct 22, 2028: Apr 30, May 14, May 28, Jun 11, More...
Carnival Cruise Lines, Carnival Firenze
Carnival Firenze3 Night - Baja Mexico
Starting in Long Beach (Los Angeles), Ca, Ensenada, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: May 5, May 8, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, More...
Lindblad Expeditions, National Geographic Sea Lion
National Geographic Sea Lion5 Night - Alaska Escape : Haines, the Inian Islands and Tracy Arm Fjord
Starting in Juneau, Tracy Arm / Fords Terror Wilderness, Haines, Icy Strait and the Inian Islands, Baranof or Chichagof Island, Sitka / Disembark
2026 Sails: May 5, May 15, Jun 4, Jul 19, Jul 29, Aug 8, Aug 18, Aug 28, More...
Lindblad Expeditions Tours, National Geographic Sea Lion Tours
National Geographic Sea Lion Tours5 Night - Alaska Escape : Haines, the Inian Islands and Tracy Arm Fjord
Starting in Juneau, Tracy Arm / Fords Terror Wilderness, Haines, Icy Strait and the Inian Islands, Baranof or Chichagof Island, Sitka / Disembark
2026 Sails: May 5, May 15, Jun 4, Jul 19, Jul 29, Aug 8, Aug 18, Aug 28, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas5 Night - Pacific Coastal Cruise
Starting in Los Angeles, California, Seattle, Washington, Victoria CA, Canada, Vancouver, British Columbia
2026 Sails: May 5, More...
Princess Cruises, Island Princess
Island Princess7 Night - Pacific Wine Country
Starting in Los Angeles, California, San Diego, California, San Francisco, California, Astoria, Oregon, Victoria CA, Vancouver, Canada
2026 Sails: May 6, More...
Windstar, Star Seeker
Star Seeker1 Night - One Day Pacific Adventure
Starting in Seattle, Vancouver
2026 Sails: May 6, More...
Carnival Cruise Lines, Carnival Miracle
Carnival Miracle7 Night - Alaska Inside Passage & Glacier
Starting in Seattle, Wa, Cruise Endicott Arm Fjord, Skagway, Ak, Juneau, Ak, Ketchikan, AK, Victoria CA, Canada, Seattle, Wa
2026 Sails: May 7, May 14, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, Jul 2, Jul 9, Jul 16, Jul 23, Jul 30, Aug 6, Aug 13, Aug 20, Aug 27, Sep 3, Sep 10, More...
Celebrity Cruises, Celebrity Edge
Celebrity Edge8 Night - Hawaii Cruise
Starting in Honolulu, Oahu, Hawaii, Hilo, Hawaii, Kailua Kona, Hawaii, Vancouver, British Columbia
2026 Sails: May 7, More...

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United States Cruise Departures