United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Regent Seven Seas, Seven Seas Explorer

7 Night - Wild Frontiers
Starting in Anchorage (Whittier), Cruising Hubbard Glacier, Sitka, Cruising Holkham Bay Glacier Fjords, Klawock, Cruising the Outside Passage, Victoria CA, Vancouver
2026 Sails: Aug 19, More...

Carnival Cruise Lines, Carnival Venezia

5 Night - Bermuda
Starting in Manhattan, New York City, Bermuda, Manhattan, New York City
2026 Sails: Aug 20, More...

Cunard Line, Queen Elizabeth

7 Night - Alaska Roundtrip from Seattle
Starting in Seattle, WA, Ketchikan, AK, Juneau, AK, Glacier Bay, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Aug 20, More...

Lindblad Expeditions, National Geographic Resolution

19 Night - Alaska to Japan : Ring of Fire to Ainu Culture
Starting in Anchorage, Alaska / Nome / Embark Ship, Pribilof Islands / St Paul Island / St George Island, Baby Islands / Dutch Harbor, Aleutian Islands, Kushiro, Japan, Muroran, Aomori, Sendai, Oarai / Mito City, Shimizu, Osaka / Disembark Ship
2026 Sails: Aug 20, More...

Lindblad Expeditions Tours, National Geographic Resolution Tours

MSC Cruises, MSC Seashore

10 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Cozumel, Mexico, Costa Maya, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, More...

Princess Tours, Island Princess Tours

13 Night - Off the Beaten Path - Tour Mb6
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 20, Sep 3, More...

Royal Caribbean, Vision of the Seas

7 Night - Bahamas Cruise
Starting in Baltimore, Maryland, Orlando (Port Canaveral), Fl, Grand Bahama Island, Bahamas, Nassau, Bahamas, Baltimore, Maryland
2026 Sails: Aug 20, More...

Silversea, Silver Moon

7 Night - Seward (Anchorage to Vancouver)
Starting in Seward (Anchorage, Alaska), Cruise Hubbard Glacier, Alaska, Juneau, Alaska, Skagway, Alaska, Sitka, Alaska, Ketchikan, Alaska, Cruise British Columbia Inside Passage, Vancouver
2026 Sails: Aug 20, More...

Virgin Voyages, Brilliant Lady

7 Night - Alaska : Inside Passage & Glacial Fjords
Starting in Seattle, Washington, Inside Passage (Cruising), Ketchikan, Alaska, Juneau, Alaska, Endicott Arm and Dawes Glacier (Cruising), Prince Rupert, Canada, Seattle, Washington
2026 Sails: Aug 20, More...

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United States Cruise Departures