United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Holland America, Nieuw Statendam

13 Night - Cultural Crossing with Paris & London
Starting in Fort Lauderdale, Florida, Kings Wharf, Bermuda, Portland UK (Weymouth), England, United Kingdom, Le Havre (Paris), France, Dover UK (London), England
2026 Sails: Apr 4, More...

Holland America, Nieuw Statendam

14 Night - Cultural Crossing with Paris & London
Starting in Fort Lauderdale, Florida, Kings Wharf, Bermuda, Portland UK (Weymouth), England, United Kingdom, Le Havre (Paris), France, Dover UK (London), England, Rotterdam, the Netherlands
2026 Sails: Apr 4, More...

Lindblad Expeditions, National Geographic Sea Bird

7 Night - Columbia and Snake Rivers : Food, Wine and History
Starting in Clarkston, Washington / Embark Ship, Clarkston, Washington, Palouse River, Walla Walla, Cruising / The Dalles / Hood River, Astoria, Portland-OR, Oregon / Disembark Ship
2026 Sails: Apr 4, Apr 18, Sep 12, Sep 26, Oct 10, Oct 24, More...

MSC Cruises, MSC Grandiosa

7 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Apr 4, More...

MSC Cruises, MSC World America

7 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 4, Apr 18, May 30, Jun 27, Jul 11, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, More...

MSC Cruises, MSC World America

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 4, May 2, May 16, May 30, Jun 13, Jun 27, Jul 25, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, Nov 14, Dec 26, 2027: Mar 6, Mar 20, More...

Norwegian Cruise Line, Norwegian Encore

7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Falmouth, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Miami, Fl
2026 Sails: Apr 4, More...

Norwegian Cruise Line, Norwegian Jade

7 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Apr 4, More...

Norwegian Cruise Line, Norwegian Luna

7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Miami, Fl
2026 Sails: Apr 4, More...

Norwegian Cruise Line, Norwegian Viva

7 Night - Caribbean
Starting in Galveston, Texas, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, Galveston, Texas
2026 Sails: Apr 4, More...

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United States Cruise Departures