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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Princess Cruises, Discovery Princess
Discovery Princess4 Night - Pacific Coastal
Starting in Los Angeles, California, Victoria CA, Vancouver, Canada
2026 Sails: May 2, More...
Princess Cruises, Grand Princess
Grand Princess4 Night - Pacific Coastal
Starting in Los Angeles, California, Victoria CA, Vancouver, Canada
2026 Sails: May 2, More...
Princess Cruises, Regal Princess
Regal Princess7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Belize City, Belize, Roatan (Mahogany Bay, Honduras), Fort Lauderdale, Florida
2026 Sails: May 2, May 16, May 30, Jun 13, Jun 27, Jul 11, Aug 8, Aug 22, More...
Princess Cruises, Regal Princess
Regal Princess14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Belize City, Belize, Roatan (Mahogany Bay, Honduras), Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Maarten, Fort Lauderdale, Florida
2026 Sails: May 2, More...
Royal Caribbean, Allure of the Seas
Allure of the Seas8 Night - Eastern Caribbean Cruise
Starting in Fort Lauderdale, Florida, Basseterre, St Kitts and Nevis, Philipsburg, St Maarten, Charlotte Amalie, St Thomas, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: May 2, More...
Royal Caribbean, Enchantment of the Seas
Enchantment of the Seas7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Belize City, Belize, Cozumel, Mexico, Tampa, Florida
2026 Sails: May 2, May 16, May 30, Jun 6, Jun 20, Jun 27, Jul 11, Aug 8, More...
Royal Caribbean, Freedom of the Seas
Freedom of the Seas5 Night - Western Caribbean Cruise
Starting in Miami, Florida, Nassau, Bahamas, Puerto Plata, Dominican Republic, Miami, Florida
2026 Sails: May 2, 2027: Feb 15, Mar 15, Mar 29, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2026 Sails: May 2, More...
Royal Caribbean, Icon of the Seas
Icon of the Seas7 Night - Western Caribbean Cruise
Starting in Miami, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Miami, Florida
2026 Sails: May 2, More...
Virgin Voyages, Resilient Lady
Resilient Lady5 Night - Grand Turk & Bimini Beach Club
Starting in Miami, Grand Turk, Turks and Caicos, The Beach Club at Bimini, Bahamas, Miami
2026 Sails: May 2, May 16, May 30, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, More...

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United States Cruise Departures