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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Belize City, Belize, Cozumel, Mexico, Tampa, Florida
2026 Sails: Jan 31, Feb 28, More...
Royal Caribbean, Rhapsody of the Seas
Rhapsody of the Seas7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Puerto Costa Maya, Mexico, Roatan, Honduras, Tampa, Florida
2026 Sails: Jan 31, Mar 28, More...
Virgin Voyages, Resilient Lady
Resilient Lady7 Night - Eastern Caribbean & Bimini Beach Club
Starting in Miami, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, The Beach Club at Bimini, Bahamas, Miami
2026 Sails: Jan 31, More...
MSC Cruises, MSC Divina
MSC Divina6 Night - Caribbean and Antilles
Starting in Miami, Grand Turk Island Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Miami
2026 Sails: Feb 1, More...
Norwegian Cruise Line, Norwegian Escape
Norwegian Escape14 Night - Caribbean
Starting in New Orleans, La, Costa Maya, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Puerto Limon, Costa Rica, Colon, Panama, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, New Orleans, La
2026 Sails: Feb 1, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem12 Night - Caribbean
Starting in Jacksonville, Florida, Grand Bahama Island, Bahamas, Great Stirrup Cay, Bahamas, St Johns AG, Antigua, Philipsburg, St Maarten, Netherland Antilles, Basseterre, Saint Kitts / Nevis, St Thomas, Vi, San Juan, Pr, Jacksonville, Florida
2026 Sails: Feb 1, More...
Princess Cruises, Regal Princess
Regal Princess7 Night - Western Caribbean with Mexico
Starting in Galveston, Texas, Cozumel, Mexico, Belize City, Belize, Roatan (Mahogany Bay, Honduras), Galveston, Texas
2026 Sails: Feb 1, More...
Princess Cruises, Sun Princess
Sun Princess7 Night - Western Caribbean with Grand Cayman
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Feb 1, More...
Princess Cruises, Sun Princess
Sun Princess14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Feb 1, More...
Regent Seven Seas, Seven Seas Mariner
Seven Seas Mariner14 Night - South Pacific Dreams
Starting in Honolulu, Nawiliwili, Kailua-Kona, Hilo, Cruising the Pacific Ocean, Cruising the South Pacific, Rangiroa, Raiatea, Bora Bora, Papeete (Tahiti)
2026 Sails: Feb 1, More...

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United States Cruise Departures