San Diego Cruise Departures
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
7 Night - Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2027 Sails: Jan 23, More...
18 Night - Circle Hawaii
Starting in San Diego, California, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kahului, Maui, Hilo, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2027 Sails: Jan 26, More...
7 Night - Cabo, Mazatlan & La Paz
Starting in San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, La Paz, Mexico, San Diego, California
2027 Sails: Jan 28, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Jan 29, More...15 Night - Panama Canal
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Miami, Florida
2027 Sails: Jan 30, More...
9 Night - San Diego City Highlights Cruisetour Package
Starting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, Ca
2027 Sails: Feb 4, More...
7 Night - Mexican Riviera Cruise from San Diego
Starting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2027 Sails: Feb 5, Mar 12, Apr 23, More...4 Night - Catalina & Ensenada Cruise
Starting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Feb 7, Mar 21, More...18 Night - San Diego City Highlights Cruisetour Package
Starting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 11, More...35 Night - Legendary Hawaii, Tahiti & Marquesas
Starting in San Diego, California, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Raiatea, Society Islands, French Polynesia, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Feb 13, More...
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2027 Sails: Jan 23, More...
18 Night - Circle HawaiiStarting in San Diego, California, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kahului, Maui, Hilo, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2027 Sails: Jan 26, More...
7 Night - Cabo, Mazatlan & La PazStarting in San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, La Paz, Mexico, San Diego, California
2027 Sails: Jan 28, More...
16 Night - Panama Canal - Ocean to OceanStarting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Jan 29, More...
15 Night - Panama CanalStarting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Miami, Florida
2027 Sails: Jan 30, More...
9 Night - San Diego City Highlights Cruisetour PackageStarting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, Ca
2027 Sails: Feb 4, More...
7 Night - Mexican Riviera Cruise from San DiegoStarting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2027 Sails: Feb 5, Mar 12, Apr 23, More...
4 Night - Catalina & Ensenada CruiseStarting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Feb 7, Mar 21, More...
18 Night - San Diego City Highlights Cruisetour PackageStarting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 11, More...
35 Night - Legendary Hawaii, Tahiti & MarquesasStarting in San Diego, California, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Raiatea, Society Islands, French Polynesia, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Feb 13, More...
