San Diego Cruises
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
29 Night - Circle Hawaii & Historical Baja Peninsula
Starting in San Diego, California, Kona, Hawaii, Honolulu, Hawaii, Kahului, Maui, Hilo, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2025 Sails: Nov 19, More...
5 Night - West Coast Getaway with San Diego
Starting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2025 Sails: Nov 26, 2026: Feb 14, More...29 Night - Historical Baja Peninsula & Circle Hawaii Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...
14 Night - Mexican Riviera & Baja Peninsula Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 20, More...24 Night - Mexico Riviera & Circle Hawaii
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California, Kahului, Maui, Hilo, Hawaii, Kona, Hawaii, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 3, More...
133 Night - Grand World Voyage
Starting in Fort Lauderdale, Florida, Bridgetown, Barbados, Devils Island, French Guiana, Crossing the Equator, Icoaraci (Belem), Brazil, Recife, Brazil, Rio De Janeiro, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Antarctic, Drake Passage and Cape Horn, Ushuaia, Argentina, Beagle Channel, Daylight cruising Glacier Alley, Punta Arenas, Chile, Strait of Magellan, Scenic cruising Amalia or Brujo Glacier, Scenic cruising Sarmiento Channel, Cruising Chilean Fjords, Puerto Montt, Chile, San Antonio CL (Santiago), Chile, Easter Island, Chile, Scenic Cruising Pitcairn Island, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Bora Bora, French Polynesia, Cross International Dateline, Nuku Alofa, Tonga, Auckland, New Zealand, Waitangi (Bay of Islands), New Zealand, Sydney AU, Townsville, Australia, Cairns, Australia, Scenic Cruising Torres Strait, Darwin, Australia, Slawi Bay, Komodo Island, Indonesia, Benoa (Denpasar), Bali, Indonesia, Crossing the Equator, Singapore, Phu My, Vietnam, Da Nang (Hue), Vietnam, Halong Bay, Vietnam, Hong Kong, China, Kaohsiung, Taiwan, Keelung (Taipei), Taiwan, Naha, Japan, Amami (Naze), Amami Oshima, Japan, Nagasaki, Japan, Shimizu, Japan, Yokohama (Tokyo), Japan, Hakodate, Japan, Cross International Dateline, Kodiak, Alaska, Sitka, Alaska, Ketchikan, Alaska, Seattle, Washington, San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Jan 4, More...
33 Night - Msc World Cruise
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Jan 4, More...131 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Jan 5, More...91 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore
2026 Sails: Jan 5, More...78 Night - Msc World Cruise
Starting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Granada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva Islas, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan
2026 Sails: Jan 5, More...
Cruises that visit North America: United States: California: San Diego
Cruises that depart from San Diego
Click on a cruise ship itinerary that visits San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
29 Night - Circle Hawaii & Historical Baja PeninsulaStarting in San Diego, California, Kona, Hawaii, Honolulu, Hawaii, Kahului, Maui, Hilo, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2025 Sails: Nov 19, More...
5 Night - West Coast Getaway with San DiegoStarting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2025 Sails: Nov 26, 2026: Feb 14, More...
29 Night - Historical Baja Peninsula & Circle Hawaii HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...
14 Night - Mexican Riviera & Baja Peninsula HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 20, More...
24 Night - Mexico Riviera & Circle HawaiiStarting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California, Kahului, Maui, Hilo, Hawaii, Kona, Hawaii, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Ensenada, Mexico, San Diego, California
2026 Sails: Jan 3, More...
133 Night - Grand World VoyageStarting in Fort Lauderdale, Florida, Bridgetown, Barbados, Devils Island, French Guiana, Crossing the Equator, Icoaraci (Belem), Brazil, Recife, Brazil, Rio De Janeiro, Brazil, Punta Del Este, Uruguay, Buenos Aires, Argentina, Montevideo, Uruguay, Port Stanley, Falkland Islands, Antarctic, Drake Passage and Cape Horn, Ushuaia, Argentina, Beagle Channel, Daylight cruising Glacier Alley, Punta Arenas, Chile, Strait of Magellan, Scenic cruising Amalia or Brujo Glacier, Scenic cruising Sarmiento Channel, Cruising Chilean Fjords, Puerto Montt, Chile, San Antonio CL (Santiago), Chile, Easter Island, Chile, Scenic Cruising Pitcairn Island, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Bora Bora, French Polynesia, Cross International Dateline, Nuku Alofa, Tonga, Auckland, New Zealand, Waitangi (Bay of Islands), New Zealand, Sydney AU, Townsville, Australia, Cairns, Australia, Scenic Cruising Torres Strait, Darwin, Australia, Slawi Bay, Komodo Island, Indonesia, Benoa (Denpasar), Bali, Indonesia, Crossing the Equator, Singapore, Phu My, Vietnam, Da Nang (Hue), Vietnam, Halong Bay, Vietnam, Hong Kong, China, Kaohsiung, Taiwan, Keelung (Taipei), Taiwan, Naha, Japan, Amami (Naze), Amami Oshima, Japan, Nagasaki, Japan, Shimizu, Japan, Yokohama (Tokyo), Japan, Hakodate, Japan, Cross International Dateline, Kodiak, Alaska, Sitka, Alaska, Ketchikan, Alaska, Seattle, Washington, San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Jan 4, More...
33 Night - Msc World CruiseStarting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Jan 4, More...
131 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore, Port Klang (Kuala Lumpur), Malaysia, Penang, Malaysia, Port Victoria, Seychelles, Port Louis, Mauritius, La Possession, Reunion, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde, Civitavecchia (Rome), Italy, Livorno (Florence), Italy, Genoa (Portofino), Italy
2026 Sails: Jan 5, More...
91 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint George, Grenada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan, Nagasaki, Japan, Busan, South Korea, Shanghai, China, Hong Kong, China, Da Nang, Vietnam, Singapore
2026 Sails: Jan 5, More...
78 Night - Msc World CruiseStarting in Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Funchal (Madeira Islands), Portugal, Bridgetown, Barbados, Saint Georges, Granada, Willemstad AN, Curacao, Cartagena CO, Puerto Limon, Costa Rica, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Hilo, Hawaii, Pago Pago, American Samoa, Apia, Western Samoa, Suva Islas, Fiji, Auckland, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Townsville, Australia, Cairns, Australia, Manila, Philippines, Keelung (Taipei) Taiwan, China, Ishigaki, Japan, Naha (Okinawa), Japan, Tokyo, Japan
2026 Sails: Jan 5, More...
