San Diego Cruise Departures
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
9 Night - San Diego City Highlights Cruisetour Package
Starting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, Ca
2027 Sails: Feb 4, More...
7 Night - Mexican Riviera Cruise from San Diego
Starting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2027 Sails: Feb 5, Mar 12, Apr 23, More...
4 Night - Catalina & Ensenada Cruise
Starting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Feb 7, Mar 21, More...18 Night - San Diego City Highlights Cruisetour Package
Starting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 11, More...
35 Night - Legendary Hawaii, Tahiti & Marquesas
Starting in San Diego, California, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Raiatea, Society Islands, French Polynesia, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Feb 13, More...16 Night - Repo - Panama Canal
Starting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 13, More...7 Night - Ensenada, Cabo & Mazatlan
Starting in San Diego, California, Ensenada, Mexico, Cabo San Lucas, Mexico, Mazatlan, Mexico, San Diego, California
2027 Sails: Feb 28, More...4 Night - Catalina & Ensenada Cruise
Starting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Mar 7, More...4 Night - Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2027 Sails: Mar 8, Mar 22, More...18 Night - Baja Peninsula, Mexican Riviera & Pacific Coast
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California, Victoria CA, Canada, Vancouver, BC, CA
2027 Sails: Mar 20, More...
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
9 Night - San Diego City Highlights Cruisetour PackageStarting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, Ca
2027 Sails: Feb 4, More...
7 Night - Mexican Riviera Cruise from San DiegoStarting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2027 Sails: Feb 5, Mar 12, Apr 23, More...
4 Night - Catalina & Ensenada CruiseStarting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Feb 7, Mar 21, More...
18 Night - San Diego City Highlights Cruisetour PackageStarting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 11, More...
Deal link -> Special
35 Night - Legendary Hawaii, Tahiti & MarquesasStarting in San Diego, California, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Raiatea, Society Islands, French Polynesia, Papeete, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Feb 13, More...
16 Night - Repo - Panama CanalStarting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 13, More...
7 Night - Ensenada, Cabo & MazatlanStarting in San Diego, California, Ensenada, Mexico, Cabo San Lucas, Mexico, Mazatlan, Mexico, San Diego, California
2027 Sails: Feb 28, More...
4 Night - Catalina & Ensenada CruiseStarting in San Diego, California, Catalina Island, California, Ensenada, Mexico, San Diego, California
2027 Sails: Mar 7, More...
4 Night - Baja Cruise from San DiegoStarting in San Diego, Ensenada, San Diego
2027 Sails: Mar 8, Mar 22, More...
Deal link -> Special
18 Night - Baja Peninsula, Mexican Riviera & Pacific CoastStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California, Victoria CA, Canada, Vancouver, BC, CA
2027 Sails: Mar 20, More...
