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Departing from San Diego Cruise Specials

We've gathered all of the Departing from San Diego cruise specials ordered by sail date. Click on a special and select a sail date to get a single cruise quote from the cruise agency that posted that particular special. To search through all cruise itineraries (not just Departing from San Diego cruises) to receive multiple custom cruise options to compare, please visit our Cruise Search page.

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Holland America, Nieuw Amsterdam
Family
Nieuw Amsterdam16 Nights Panama Canal Cruise from $1715 pp plus OBC
16 Night - Panama Canal - Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 2 Get a Quote
Holland America, Koningsdam
Discount
Koningsdam7 Nights Mediterranean Cruise from $821 pp plus OBC
7 Night - Classic California Coast - Starting in San Diego, California, Avalon, California, San Francisco, California, Ensenada, Mexico, San Diego, California
2026 Sails: Nov 14 Get a Quote
Royal Caribbean, Serenade of the Seas
Discount
Serenade of the Seas7 Nights Cabo, Mazatlan & La Paz Cruise from $828 pp plus OBC
7 Night - Cabo, Mazatlan & La Paz Cruise - Starting in San Diego, California, Cabo San Lucas, Mexico, La Paz, Mexico, Mazatlan, Mexico, San Diego, California
2026 Sails: Nov 22 Get a Quote
Royal Caribbean, Serenade of the Seas
Family
Serenade of the Seas7 Nights Mexico Cruise from $749 pp plus OBC
7 Night - Cabo, Mazatlan & La Paz Cruise - Starting in San Diego, California, Cabo San Lucas, Mexico, La Paz, Mexico, Mazatlan, Mexico, San Diego, California
2026 Sails: Nov 22, Dec 20 Get a Quote
Holland America, Zaandam
Family
Zaandam12 Nights Historical Baja Peninsula Cruise from $1035 pp plus OBC
12 Night - Historical Baja Peninsula - Starting in San Diego, California, Cabo San Lucas, Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Dec 7 Get a Quote
Norwegian Cruise Line, Norwegian Star
Family
Norwegian Star7 Nights Mexican Riviera Round-trip San Diego Cruise from $577 pp
7 Night - Mexican Riviera - San Diego - Starting in San Diego, Ca, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, Ca
2026 Sails: Dec 26
2027 Sails: Feb 6 Get a Quote
Norwegian Cruise Line, Norwegian Star
Family
Norwegian Star7 Nights Mexican Riviera Round-trip San Diego Cruise from $559 pp
7 Night - Mexican Riviera - San Diego - Starting in San Diego, Ca, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, San Diego, Ca
2027 Sails: Jan 2, Jan 30 Get a Quote
Norwegian Cruise Line, Norwegian Star
Family
Norwegian Star7 Nights Mexican Riviera Round-trip San Diego Cruise from $559 pp
7 Night - Mexican Riviera - San Diego - Starting in San Diego, Ca, Mazatlan, Mexico, Cabo San Lucas, Mexico, Ensenada, Mexico, San Diego, Ca
2027 Sails: Jan 9, Jan 16, Jan 23 Get a Quote
Norwegian Cruise Line, Norwegian Star
Family
Norwegian Star16 Nights Panama Canal from San Diego to Miami Cruise from $1814 pp
16 Night - Repo - Panama Canal - Starting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 13 Get a Quote

Departing from San Diego Cruise Specials