Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Disney Cruise Line, Disney Magic
Disney Magic Cruise Ship3 Night - Halloween On the High Seas Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2026 Sails: Sep 28, Oct 16, More...
Disney Cruise Line, Disney Magic
Disney Magic Cruise Ship4 Night - Halloween On the High Seas Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Oct 1, More...
Holland America Line, Nieuw Amsterdam
Nieuw Amsterdam Cruise Ship16 Night - Panama Canal
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 2, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship2 Night - Ensenada Cruise
Starting in San Diego, California, Ensenada, Mexico, San Diego, California
2026 Sails: Oct 2, More...
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship7 Night - Halloween On the High Seas Mexican Riviera Cruise from San Diego
Starting in San Diego, Puerto Vallarta, Cabo San Lucas, Ensenada, San Diego
2026 Sails: Oct 3, More...
Royal Caribbean International, Serenade of the Seas
Serenade of the Seas Cruise Ship7 Night - Ensenada, Cabo & La Paz Cruise
Starting in San Diego, California, La Paz, Mexico, Cabo San Lucas, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Oct 4, Oct 25, More...
Disney Cruise Line, Disney Magic
Disney Magic Cruise Ship4 Night - Halloween On the High Seas Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Oct 5, More...
Holland America Line, Eurodam
Eurodam Cruise Ship16 Night - Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 8, More...
Holland America Line, Zaandam
Zaandam Cruise Ship7 Night - Mexican Riviera
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2026 Sails: Oct 8, More...
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship3 Night - Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2026 Sails: Oct 10, Dec 15, 2027: Feb 12, Feb 26, More...

<= Back
More =>

San Diego Cruise Departures