Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Cunard Line, Queen Victoria

14 Night - Italy and Adriatic
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Stromboli Sail By, IT, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Jun 29, More...

Cunard Line, Queen Victoria

21 Night - Greece, Adriatic and Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Stromboli Sail By, IT, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Jun 29, More...

Explora Journeys, EXPLORA I

7 Night - A Journey of Shimmering Shores & Timeless Mediterranean Treasures
Starting in Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona
2026 Sails: Jun 29, Jul 27, Aug 24, Sep 21, More...

Explora Journeys, EXPLORA I

14 Night - An Extended Journey Through Mediterranean Grandeur
Starting in Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona, Palma De Mallorca, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome)
2026 Sails: Jun 29, More...

Royal Caribbean, Brilliance of the Seas

7 Night - Italy, Croatia & the Adriatic
Starting in Ravenna, Italy, Koper, Slovenia, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jun 29, Aug 10, More...

Sea Cloud, Sea Cloud Spirit

9 Night - Western Mediterranean from Livorno to Malaga
Starting in Livorno, Alghero / Sardinia, Mahon / Menorca, Ibiza City / Ibiza, Malaga
2026 Sails: Jun 29, More...

Celebrity Cruises, Celebrity Equinox

9 Night - Italian Riviera & France
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: Jun 30, More...

Norwegian Line Tours, Norwegian Viva Tours

13 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Piraeus / Athens, Greece, Kusadasi, Turkey, Rhodes, Greece, Santorini Island, Greece, Istanbul, Turkey
2026 Sails: Jun 30, More...

Atlas Ocean Voyages, World Traveller

9 Night - Rome to Athens
Starting in Civitavecchia (Rome), Sorrento, Italy, Lipari (Aeolian Islands), Italy, Chania (Crete), Greece, Agios Nikolaos (Crete), Kusadasi (Ephesus), Patmos, Naousa (Paros), Piraeus (Athens)
2026 Sails: Jul 1, More...

Norwegian Line Tours, Norwegian Gem Tours

10 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Olympia / Katakolon, Greece, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Jul 2, Sep 24, More...

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