Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Oceania Cruises, Oceania Insignia

10 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Sorrento / Capri, Messina (Sicily), Valletta, Crotone (Calabria), Corfu, Kotor, Dubrovnik, Croatia, Zadar, Koper, Venice (Fusina)
2026 Sails: Oct 13, More...

Ritz-Carlton, Ilma

7 Night - Rome (Civitavecchia) / Barcelona
Starting in Rome (Civitavecchia), Livorno, Monte Carlo, Saint-Tropez, Palma de Mallorca, Mallorca, Balearic Islands, Barcelona
2026 Sails: Oct 13, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean Roundtrip from Cagliari
Starting in Cagliari, Palermo, Civitavecchia (Rome), Savona, Marseille, Barcelona, Cagliari
2026 Sails: Oct 14, More...

Viking Ocean, Viking Jupiter

Deal link -> Special

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Oct 14, 2027: Oct 2, 2028: Jun 17, Jul 29, More...

Viking Ocean, Viking Vesta

12 Night - Mediterranean Odyssey
Starting in Venice (Fusina), Split, Dubrovnik, Croatia, Corfu (Kerkyra), Sail the Ionian Sea, Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Barcelona
2026 Sails: Oct 15, More...

Windstar, Wind Surf

23 Night - Star Collector : Riviera Rhapsody
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome, Portofino, Monte Carlo, Sanary-sur-mer, Palamos, Barcelona, Palma De Mallorca, Cartagena ES, Almeria, Spain, Malaga, Gibraltar, Cadiz, Lisbon
2026 Sails: Oct 15, More...

Windstar, Wind Surf

15 Night - Star Collector : Italian Trio
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome, Portofino, Monte Carlo, Sanary-sur-mer, Palamos, Barcelona
2026 Sails: Oct 15, More...

Windstar, Wind Surf

10 Night - Classic Italy & Dalmatian Coast
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome
2026 Sails: Oct 15, More...

Windstar Tours, Wind Surf Tours

13 Night - Vatican & Croatian Coastlines Cruise Tour
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome
2026 Sails: Oct 15, More...

MSC Cruises, MSC Meraviglia

4 Night - Mediterranean
Starting in Palermo (Monreale), Italy, Naples (Pompeii), Italy, Livorno (Florence), Italy, Marseille (Provence), France, Barcelona, Spain
2026 Sails: Oct 16, More...

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