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Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Departing from
Italy
Cruise Specials

Viking Ocean, Viking Mira
Viking Mira7 Night - Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Nov 11, 2028: Mar 16, More...
Viking Ocean, Viking Sky
Viking Sky7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Nov 11, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda10 Night - Western Mediterranean from Savona to Santa Cruz de Tenerife
Starting in Savona, Marseille, Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Nov 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda11 Night - Transatlantic from Savona
Starting in Savona, Marseille, Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife
2026 Sails: Nov 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda14 Night - Western Mediterranean from Savona to Las Palmas
Starting in Savona, Marseille, Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife, Port Rosario (Fuerteventura), Arrecife (Lanzarote), Las Palmas (Gran Canaria)
2026 Sails: Nov 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda7 Night - Western Mediterranean from Savona to Santa Cruz de Tenerife
Starting in Savona, Marseille, Barcelona, Malaga, Cadiz, Las Palmas (Gran Canaria)
2026 Sails: Nov 12, More...
Costa Cruise Lines, Costa Smeralda
Costa Smeralda2 Night - Europe from Savona to Barcelona
Starting in Savona, Marseille, Barcelona
2026 Sails: Nov 12, More...
MSC Cruises, MSC Splendida
MSC Splendida21 Night - Msc Grand Voyages
Starting in Palermo (Monreale), Italy, La Valletta, Malta, Barcelona, Spain, Gibraltar, Casablanca (Marrakesh), Morocco, Las Palmas de Gran Canaria (Canary Islands), Spain, Maceio, Brazil, Salvador, Brazil, Rio De Janeiro, Brazil, Montevideo, Uruguay, Buenos Aires, Argentina
2026 Sails: Nov 12, More...
Silversea, Silver Nova
Silver Nova10 Night - Fusina to Civitavecchia
Starting in Fusina (Venice), Trieste, Kotor, Bari, Valletta, Giardini Naxos (Sicily), Palermo, Sicily, Naples, Civitavecchia (Rome)
2026 Sails: Nov 13, More...
Costa Cruise Lines, Costa Deliziosa
Costa Deliziosa6 Night - Eastern Mediterranean from Trieste
Starting in Trieste, Bari, Corfu, Siracusa, Malta / La Valletta, Trieste
2026 Sails: Nov 14, More...

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Italy Cruise Departures