Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Costa Cruise Lines, Costa Pacifica

7 Night - Western Mediterranean from Savona
Starting in Savona, La Seyne (St Tropez), Palma De Mallorca, Valencia, Olbia, Civitavecchia (Rome), Savona
2026 Sails: May 17, May 24, Jun 21, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Venice / Marghera, Italy, Zadar, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy
2026 Sails: May 17, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Eastern Mediterranean
Starting in Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Koper, Slovenia, Venice (Ravenna), Italy
2026 Sails: May 17, May 31, Jun 28, Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, More...

Norwegian Cruise Line, Norwegian Pearl

7 Night - Europe - Greek Isles - Venice
Starting in Venice (Ravenna), Italy, Zadar, Croatia, Kotor, Montenegro, Corfu, Greece, Olympia / Katakolon, Greece, Mykonos, Greece, Santorini Island, Greece, Piraeus / Athens, Greece
2026 Sails: May 17, More...

Celebrity Cruises, Celebrity Constellation

11 Night - Best of Italy & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (La Spezia), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Dubrovnik, Croatia, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: May 18, More...

Costa Cruise Lines, Costa Fascinosa

14 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Catania, Athens (Piraeus), Heraklion, Mykonos, Santorini, Malta / La Valletta, Ibiza, Barcelona, Marseille, Savona, Civitavecchia (Rome)
2026 Sails: May 18, More...

Explora Journeys, EXPLORA II

7 Night - A Journey to Adriatic Wonders & Whispered Ancient Secrets
Starting in Fusina (Venice), Rovinj, Dubrovnik, Croatia, Brindisi, Kotor, Milos, Piraeus (Athens)
2026 Sails: May 18, Jul 20, Sep 21, Oct 12, More...

Explora Journeys, EXPLORA II

14 Night - An Extended Journey of Quiet Shores & Endless Blue
Starting in Fusina (Venice), Rovinj, Dubrovnik, Croatia, Brindisi, Kotor, Milos, Piraeus (Athens), Mykonos, Katapola, Pylos, Nydri, Lefkada, Bodrum, Bari, Piraeus (Athens)
2026 Sails: May 18, More...

Royal Caribbean, Brilliance of the Seas

7 Night - Italy, Croatia & the Adriatic
Starting in Ravenna, Italy, Trieste, Italy, Split, Croatia, Dubrovnik, Croatia, Sarande, Albania, Amalfi Coast (Salerno), Italy, Rome (Civitavecchia), Italy
2026 Sails: May 18, More...

Costa Cruise Lines, Costa Fascinosa

18 Night - Western Mediterranean from Catania
Starting in Catania, Athens (Piraeus), Heraklion, Mykonos, Santorini, Malta / La Valletta, Ibiza, Barcelona, Marseille, Savona, Civitavecchia (Rome), Napoli, Palermo, La Goulette, Malta / La Valletta, Catania
2026 Sails: May 19, More...

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