Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Lecce : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Atlas Ocean Voyages, World Traveller

9 Night - Rome to Athens
Starting in Civitavecchia (Rome), Sorrento, Italy, Lipari (Aeolian Islands), Italy, Chania (Crete), Greece, Agios Nikolaos (Crete), Kusadasi (Ephesus), Patmos, Naousa (Paros), Piraeus (Athens)
2026 Sails: Jul 1, More...

MSC Cruises, MSC Divina

7 Night - Mediterranean
Starting in Naples (Pompeii), Italy, Civitavecchia (Rome), Italy, Mykonos, Greece, Kusadasi, Turkey, Marmaris, Turkey, Naples (Pompeii), Italy
2026 Sails: Jul 2, Oct 1, 2027: Sep 16, More...

Oceania Cruises, Oceania Nautica

10 Night - Mediterranean Medley
Starting in Rome (Civitavecchia), Salerno, Taormina (Sicily), Valletta, Ibiza, Valencia, Barcelona, Provence (Marseille), Cannes, Monte Carlo
2026 Sails: Jul 2, More...

Star Clippers, Star Clipper

11 Night - Italy, Montenegro, Croatia
Starting in Venice, Italy, Mali Losinj, Croatia, Sibenik, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Otranto, Italy, Taormina, Sicily, Italy, Lipari / Aeolian Islands, Italy, Amalfi, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy
2026 Sails: Jul 2, Aug 20, More...

Viking Ocean, Viking Star

9 Night - Empires of the Mediterranean
Starting in Venice (Chioggia), Koper, Zadar, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Santorini (Thira), Athens (Piraeus)
2026 Sails: Jul 2, More...

Norwegian Cruise Line, Norwegian Viva

10 Night - Greek Isles & Italy
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Montenegro, Piraeus / Athens, Greece, Kusadasi, Turkey, Rhodes, Greece, Santorini Island, Greece, Istanbul, Turkey
2026 Sails: Jul 3, More...

Silversea, Silver Muse

9 Night - Fusina to Fusina
Starting in Fusina (Venice), Trieste, Rovinj, Kotor, Bari, Dubrovnik, Croatia, Hvar, Zadar, Fusina (Venice)
2026 Sails: Jul 3, More...

Emerald Cruises, Emerald Kaia

14 Night - Discover the Gems of Italy & Croatia
Starting in Venice, Italy, Piran, Slovenia, Mali Losinj, Croatia, Senj, Croatia / Baska, Krk Island, Croatia, Opatija, Croatia, Rovinj, Croatia, Venice, Italy, Rovinj, Croatia, Sibenik, Croatia, Trogir, Croatia, Vis / Hvar, Croatia, Hvar, Croatia, Korcula, Croatia, Dubrovnik, Croatia
2026 Sails: Jul 4, Jul 25, More...

Emerald Cruises, Emerald Sakara

7 Night - Enchanting Italian Coastlines
Starting in Civitavecchia (Rome), Italy, Amalfi, Italy / Capri, Italy, Capri, Italy / Sorrento, Italy, Sorrento, Italy, Gaeta, Italy, Porto Cervo, Italy, Bonifacio, France, Civitavecchia (Rome), Italy
2026 Sails: Jul 4, Aug 8, 2027: Aug 28, More...

Princess Cruises, Sun Princess

7 Night - Mediterranean with Italy & Turkey
Starting in Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Jul 4, Jul 25, Aug 15, Sep 5, Sep 26, Oct 17, 2027: Apr 18, May 9, May 30, Aug 22, Sep 12, Oct 3, Oct 24, More...

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