Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Lecce : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Azamara Cruises, Azamara Onward

9 Night - Croatia Intensive Cruise : Dubrovnik, Sibenik & Zadar
Starting in Venice (Fusina), Opatija, Zadar, Sibenik, Korcula, Dubrovnik, Croatia, Kotor, Corfu, Athens (Piraeus)
2026 Sails: Jun 29, More...

Cunard Line, Queen Victoria

7 Night - Italy and Adriatic
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy
2026 Sails: Jun 29, Aug 24, More...

Cunard Line, Queen Victoria

14 Night - Italy and Adriatic
Starting in Civitavecchia (tours to Rome), Italy, Messina Strait, Italy (Transit), Cephalonia, Greece, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Stromboli Sail By, IT, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Jun 29, More...

Explora Journeys, EXPLORA I

7 Night - A Journey of Shimmering Shores & Timeless Mediterranean Treasures
Starting in Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona
2026 Sails: Jun 29, Jul 27, Aug 24, Sep 21, More...

Explora Journeys, EXPLORA I

14 Night - An Extended Journey Through Mediterranean Grandeur
Starting in Civitavecchia (Rome), Port of Naples, Capri, Calvi (Corsica), Villefranche-Sur-Mer (Nice), Marseille, Mahon (Menorca), Barcelona, Palma De Mallorca, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome)
2026 Sails: Jun 29, More...

Royal Caribbean, Brilliance of the Seas

7 Night - Italy, Croatia & the Adriatic
Starting in Ravenna, Italy, Koper, Slovenia, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jun 29, More...

Sea Cloud, Sea Cloud Spirit

9 Night - Western Mediterranean from Livorno to Malaga
Starting in Livorno, Alghero / Sardinia, Mahon / Menorca, Ibiza City / Ibiza, Malaga
2026 Sails: Jun 29, More...

Celebrity Cruises, Celebrity Equinox

9 Night - Italian Riviera & France
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Portofino, Italy, Florence / Pisa (La Spezia), Italy, Nice (Villefranche), France, Provence (Marseille), France, Barcelona, Spain
2026 Sails: Jun 30, More...

Princess Cruises, Enchanted Princess

7 Night - Mediterranean & Adriatic
Starting in Civitavecchia (for Rome), Italy, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy
2026 Sails: Jun 30, Jul 14, Jul 28, Aug 25, Sep 8, Oct 6, More...

Princess Cruises, Enchanted Princess

14 Night - Mediterranean, Aegean & Adriatic
Starting in Civitavecchia (for Rome), Italy, Corfu, Greece, Dubrovnik, Croatia, Kotor, Montenegro, Naples, Italy (for Capri and Pompeii), Civitavecchia (for Rome), Italy, Amalfi Coast (Salerno), Santorini, Greece, Kusadasi, Turkey (for Ephesus), Katakolon (for Olympia), Greece, Civitavecchia (for Rome), Italy
2026 Sails: Jun 30, Jul 14, Aug 25, Oct 6, More...

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