Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Windstar, Wind Surf

15 Night - Star Collector : Iconic Italy and Croatia
Starting in Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Sorrento, Rome, Bastia, Cannes, Monte Carlo, Genoa, Italy, Portofino, Porto Ercole, Rome
2026 Sails: Aug 18, More...

MSC Cruises, MSC Fantasia

9 Night - Mediterranean
Starting in Trieste (Venice), Italy, Katakolon (Olympia), Greece, Santorini, Greece, Piraeus (Athens), Greece, Istanbul, Turkey, Corfu, Greece, Bari, Italy, Trieste (Venice), Italy
2026 Sails: Aug 19, More...

PONANT, Le Bougainville

7 Night - Natural Wonders and Cultural Jewels of Dalmatia
Starting in Venice, Rovinj, Zadar, Primosten, Split, Hvar, Korcula, Mljet, Tivat, Dubrovnik, Croatia
2026 Sails: Aug 20, More...

Royal Caribbean, Legend of the Seas

7 Night - Western Mediterranean Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 20, More...

Star Clippers, Star Clipper

16 Night - Grand Voyage : Venice to Rome
Starting in Venice, Italy, Mali Losinj, Croatia, Sibenik, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Otranto, Italy, Taormina, Sicily, Italy, Lipari / Aeolian Islands, Italy, Amalfi, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy, Amalfi, Italy, Sorrento, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy
2026 Sails: Aug 20, More...

Star Clippers, Star Clipper

11 Night - Italy, Montenegro, Croatia
Starting in Venice, Italy, Mali Losinj, Croatia, Sibenik, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Otranto, Italy, Taormina, Sicily, Italy, Lipari / Aeolian Islands, Italy, Amalfi, Italy, Ponza / Pontine Islands, Italy, Civitavecchia (Port for Rome), Italy
2026 Sails: Aug 20, More...

Celebrity Cruises, Celebrity Constellation

10 Night - Best of Italy & Croatia Cruise
Starting in Ravenna, Italy, Split, Croatia, Dubrovnik, Croatia, Kotor, Montenegro, Sicily (Messina), Italy, Amalfi Coast (Salerno), Italy, Portofino, Italy, Florence / Pisa (Livorno), Italy, Rome (Civitavecchia), Italy
2026 Sails: Aug 21, More...

Costa Cruise Lines, Costa Deliziosa

14 Night - Eastern Mediterranean from Marghera
Starting in Marghera (Venice), Bari, Corfu, Argostoli (Cephalonia), Dubrovnik, Croatia, Kotor, Zadar, Marghera (Venice), Bari, Thira (Santorini), Mykonos, Katakolon (Olympia), Marghera (Venice)
2026 Sails: Aug 22, More...

Royal Caribbean, Explorer of the Seas

7 Night - Greece & Adriatic Cruise
Starting in Ravenna, Italy, Bay of Kotor (Cruising), Kotor, Montenegro, Athens (Piraeus), Greece, Santorini, Greece, Split, Croatia, Ravenna, Italy
2026 Sails: Aug 22, More...

Virgin Voyages, Scarlet Lady

9 Night - Italy & French Riviera
Starting in Civitavecchia (Rome), Italy, Catania, Sicily, Italy, Naples, Italy, Ajaccio, Corsica, France, Cannes, France, Livorno (Florence / Pisa), Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 22, More...

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