Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Princess Cruises, Sapphire Princess

26 Night - Grand European Explorer
Starting in Civitavecchia (for Rome), Italy, Sardinia (Cagliari), Italy, Cartagena ES, Gibraltar, La Coruna, Spain (for Santiago de Compostela), Bilbao, Le Havre (for Paris / Normandy), France, Dover UK (for London), England, Oslo, Norway, Skagen, Denmark, Copenhagen, Denmark, Skagen, Denmark, Oslo, Norway, Gdansk (Gdynia), Poland, Klaipeda, Lithuania, Riga, Latvia, Tallinn, Estonia, Helsinki, Finland, Nynashamn (for Stockholm), Sweden, Visby, Sweden, Copenhagen, Denmark
2026 Sails: Apr 19, More...

Viking Ocean, Viking Sea

21 Night - Adriatic & Mediterranean Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus), Crete (Heraklion), Rhodes, Ephesus (Kusadasi), Troy (Canakkale), Istanbul
2026 Sails: Apr 19, More...

Viking Ocean, Viking Sea

14 Night - Italy, the Adriatic & Greece
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Apr 19, More...

Viking Ocean, Viking Sea

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Apr 19, More...

MSC Cruises, MSC Musica

7 Night - Mediterranean
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy
2026 Sails: Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, Jun 8, Jun 15, Jun 22, Jun 29, Jul 6, Jul 13, Jul 20, Jul 27, Aug 3, Aug 10, Aug 17, Aug 24, Aug 31, Sep 7, More...

MSC Cruises, MSC Splendida

7 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy
2026 Sails: Apr 20, More...

MSC Cruises, MSC Splendida

8 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Palermo (Monreale), Italy, La Goulette, Tunisia, Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy
2026 Sails: Apr 20, More...

MSC Cruises, MSC World Europa

7 Night - Mediterranean
Starting in Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Naples (Pompeii), Italy
2026 Sails: Apr 20, Apr 27, May 4, May 11, May 25, Jun 1, Jun 8, Jun 15, Jun 22, Jun 29, Jul 6, Jul 13, Jul 20, Jul 27, Aug 3, Aug 10, Aug 17, Aug 24, Aug 31, Sep 7, Sep 14, Sep 21, Sep 28, Oct 5, More...

Viking Ocean, Viking Mars

7 Night - Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia)
2026 Sails: Apr 20, More...

Viking Ocean, Viking Mars

14 Night - Mediterranean & Italian Sojourn
Starting in Venice (Fusina), Sibenik, Bari, Crotone, Sicily (Messina), Naples, Rome (Civitavecchia), Florence / Pisa (Livorno), Monte Carlo, Marseille, Sete, Barcelona
2026 Sails: Apr 20, More...

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