Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Royal Caribbean, Explorer of the Seas

7 Night - Greek Isles Cruise
Starting in Ravenna, Italy, Santorini, Greece, Athens (Piraeus), Greece, Mykonos, Greece, Argostoli, Greece, Ravenna, Italy
2026 Sails: Aug 1, Aug 29, More...

Windstar, Wind Surf

8 Night - Bella Italia - a Southern Italian Romance
Starting in Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice
2026 Sails: Aug 1, More...

Windstar, Wind Surf

17 Night - Star Collector : Italian Charms & Croatian Coastlines
Starting in Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice, Rovinj, Zadar, Hvar, Kotor, Dubrovnik, Croatia, Piran, Venice
2026 Sails: Aug 1, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Europe - Adriatic & Greece - Venice
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Split, Croatia, Corfu, Greece, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Aug 2, More...

Silversea, Silver Nova

7 Night - Fusina to Athens
Starting in Fusina (Venice), Zadar, Hvar, Dubrovnik, Croatia, Katakolon (Olympia), Gythion, Athens (Piraeus)
2026 Sails: Aug 2, More...

Cunard Line, Queen Victoria

Deal link -> Special

7 Night - Italy and Adriatic
Starting in Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 3, More...

Cunard Line, Queen Victoria

14 Night - Adriatic and Western Mediterranean
Starting in Trieste, Italy, Zadar, Croatia, Dubrovnik, Croatia, Valletta, Malta, Naples (tours to Capri or Pompeii), Italy, Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain
2026 Sails: Aug 3, More...

MSC Cruises, MSC Musica

7 Night - Mediterranean
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy
2026 Sails: Aug 3, More...

Oceania Cruises, Oceania Nautica

7 Night - Mediterranean Vistas
Starting in Rome (Civitavecchia), Sorrento / Capri, Taormina (Sicily), Corfu, Kotor, Split, Koper, Venice (Fusina)
2026 Sails: Aug 3, More...

Avalon Waterways Tours, Avalon Vista Tours

11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Aug 4, Aug 18, Sep 15, Sep 29, Oct 13, Oct 27, More...

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