Louisiana River Cruise Departures
River Cruises that depart from North America: United States: Louisiana
River Cruises that visit Louisiana
See all Cruises that depart from Louisiana
River cruises by river name
Related areas: New Orleans
7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2025 Sails: Dec 6, 2026: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2025 Sails: Dec 12, Dec 26, 2026: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 3, Jan 10, Jan 17, Jan 24, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 28, More...7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 31, 2027: Jan 19, More...7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 7, 2027: Jan 26, More...
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
River Cruises that depart from North America: United States: Louisiana
River Cruises that visit Louisiana
See all Cruises that depart from Louisiana
Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: New Orleans
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2025 Sails: Dec 6, 2026: Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Sep 19, Oct 3, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 18, Jun 1, Oct 12, Nov 23, Dec 7, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2025 Sails: Dec 12, Dec 26, 2026: Mar 31, Apr 14, Jul 7, Sep 1, Nov 10, Nov 24, Dec 8, Dec 22, Dec 24, 2027: Feb 10, Feb 24, Mar 30, Apr 13, Sep 24, 2028: Sep 23, Nov 18, Dec 2, More...
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 3, Jan 10, Jan 17, Jan 24, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 28, More...
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 31, 2027: Jan 19, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Feb 7, 2027: Jan 26, More...
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 16, Feb 22, Feb 28, Mar 6, Mar 12, 2027: Feb 18, Feb 24, Mar 2, Mar 8, Mar 14, Mar 20, Nov 26, Dec 2, Dec 8, Dec 14, 2028: Feb 20, Feb 26, Mar 15, Mar 21, Dec 9, Dec 15, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Jul 13, Nov 2, 2028: Feb 23, Mar 8, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
