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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Balboa : Barro Colorado Island : Bocas del Toro : Cayos Limones : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Explora Journeys, EXPLORA III
EXPLORA III10 Night - A Journey Through Enchanting Nature & the Marvels of the Panama Canal
Starting in Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 12, More...
Explora Journeys, EXPLORA III
EXPLORA III21 Night - An Extended Journey from Majestic Horizons to Mayan Gems
Starting in Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador), Acajutla, Puerto Quetzal, Puerto Madero, Huatulco (Santa Maria Huatulco), Puerto Vallarta, Los Angeles
2027 Sails: Apr 12, More...
Seabourn, Seabourn Quest
Seabourn Quest45 Night - World Cruise : South Pacific & Panama Canal
Starting in Brisbane, Australia, Norfolk Island, Australia, Noumea, New Caledonia, Mystery Island, Vanuatu, Lautoka, Fiji, Suva, Viti Levu, Fiji, Savusavu, Vanua Levu, Fiji, Apia, Upolu, Samoa, Cross International Dateline, Crossing the Equator, Honolulu, Hawaii, Kona, Hawaii, Long Beach, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Miami, Florida
2027 Sails: Apr 15, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit15 Night - Panama Canal Westward Cruise
Starting in Tampa, Florida, George Town, Grand Cayman, Cartagena CO, Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Apr 18, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy15 Night - Repo - Panama Canal
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2027 Sails: Apr 21, More...
Disney Cruise Line, Disney Magic
Disney Magic14 Night - Westbound Panama Canal Cruise from Galveston Ending in San Diego
Starting in Galveston, Cozumel, Mexico, Cartagena ES, Panama Canal, Cabo San Lucas, Ensenada, San Diego
2027 Sails: Apr 25, More...
Seabourn, Seabourn Quest
Seabourn Quest19 Night - World Cruise : Panama Canal Crossing
Starting in Long Beach, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Miami, Florida
2027 Sails: May 11, More...
Azamara Cruises, Azamara Quest
Azamara Quest17 Night - Panama Canal & Latin America Cruise : Mexico, Costa Rica & Colombia
Starting in San Diego, Cabo San Lucas, Acapulco, Puerto Quetzal, Acajutla, Puntarenas, Panama Canal (Cruising), Cartagena CO, Miami, Florida
2027 Sails: May 24, More...
Azamara Cruises, Azamara Quest
Azamara Quest35 Night - San Diego to London Grand Voyage
Starting in San Diego, Cabo San Lucas, Acapulco, Puerto Quetzal, Acajutla, Puntarenas, Panama Canal (Cruising), Cartagena CO, Miami, Florida, New York City, New York, Newport, Rhode Island, Cape Cod Canal Cruising, Boston, Massachusetts, Halifax, Nova Scotia, St Johns NF, Newfoundland, Cobh, Plymouth, England, Le Havre, London (Tilbury), England
2027 Sails: May 24, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity32 Night - The Americas & Caribbean
Starting in Vancouver, Victoria CA, Canada, Astoria, San Francisco, Santa Catalina Island, San Diego, Puerto Vallarta, Manzanillo, Zihuatanejo, Acajutla, San Juan del Sur, Puntarenas, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Port Antonio, Montego Bay, George Town (Grand Cayman), Miami, Port Canaveral, Norfolk, New York
2027 Sails: Aug 2, More...

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Panama Cruises