United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Tours, Grand Princess Tours

11 Night - Denali Explorer - Tour Db4
Starting in Anchorage, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 25, More...

Oceania Cruises, Oceania Riviera

10 Night - Inside Passage Discovery
Starting in Seattle, Ketchikan, Juneau, Sitka, Haines, Icy Strait Point (Hoonah), Cruising Holkham Bay Glacier Fjords, Wrangell, Cruising the Inside Passage, Vancouver
2026 Sails: Aug 26, More...

Princess Tours, Discovery Princess Tours

17 Night - Connoisseur Escorted - Tour Vb1
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 26, More...

Princess Tours, Grand Princess Tours

10 Night - On Your Own - Tour Bbx
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 26, More...

Princess Tours, Grand Princess Tours

10 Night - Denali Explorer - Tour Ab3
Starting in Anchorage, Mount Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 26, More...

American Cruise Lines, American Patriot

8 Night - Great Lakes & Thousand Islands Cruise
Starting in Buffalo, NY, Day of Cruising, Day of Cruising the Welland Canal, Rochester, NY, Clayton, NY, Day of Cruising, Ogdensburg, NY, Oswego, NY
2026 Sails: Aug 27, Oct 4, 2027: Jun 16, Aug 14, Sep 28, Oct 12, 2028: Jun 15, Aug 13, Sep 27, Oct 11, More...

Cunard Line, Queen Elizabeth

11 Night - Alaska Roundtrip from Seattle
Starting in Seattle, WA, Ketchikan, AK, Icy Strait Point, AK, Glacier Bay, AK, (Scenic Cruising), Hubbard Glacier, AK, (Scenic Cruising), Juneau, AK, Haines, AK, Sitka, AK, Victoria CA, Canada, Seattle, WA
2026 Sails: Aug 27, More...

Norwegian Cruise Line, Norwegian Jewel

Deal link -> Special

9 Night - Bermuda-Philadelphia
Starting in Philadelphia, Pa, Royal Naval Dockyard, Bermuda, Saint John NB (Bay of Fundy), Halifax, Canada, Philadelphia, Pa
2026 Sails: Aug 27, More...

Royal Caribbean, Independence of the Seas

7 Night - Bermuda Cruise
Starting in Cape Liberty, Nj (Ny Metro), Royal Naval Dockyard, Bermuda, Cape Liberty, Nj (Ny Metro)
2026 Sails: Aug 27, More...

Royal Caribbean, Vision of the Seas

9 Night - Canada & New England Cruise
Starting in Baltimore, Maryland, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Nova Scotia, Baltimore, Maryland
2026 Sails: Aug 27, More...

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United States Cruise Departures