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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Disney Cruise Line, Disney Wonder
Disney Wonder4 Night - Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Apr 20, More...
Holland America, Eurodam
Eurodam4 Night - Pacific Coastal Cruise
Starting in San Diego, California, Avalon, California, Vancouver, BC, CA
2026 Sails: Apr 20, More...
Margaritaville at Sea, Margaritaville Paradise
Margaritaville Paradise4 Night - Key West & Grand Bahama
Starting in Port of Palm Beach, Key West, FL, Freeport, Grand Bahama, Port of Palm Beach
2026 Sails: Apr 20, May 11, Jun 1, Jun 15, Aug 3, Sep 21, Sep 28, Oct 15, Oct 23, Nov 23, 2027: Jan 11, Mar 1, Mar 29, Apr 19, May 10, May 17, May 31, Jun 14, Jul 12, Jul 26, Aug 16, Sep 13, Oct 4, Oct 11, More...
MSC Seaside4 Night - Caribbean and Antilles
Starting in Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Apr 20, Apr 27, May 4, May 11, May 18, May 25, Jun 1, Jun 8, Jun 15, Jun 22, Jun 29, Jul 6, Jul 13, Jul 20, Jul 27, Aug 3, Aug 10, Aug 17, Aug 24, Aug 31, Sep 7, Sep 14, Sep 21, Sep 28, More...
Norwegian Cruise Line, Norwegian Getaway
Norwegian Getaway4 Night - Bahamas - Short
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Nassau, Bahamas, Miami, Fl
2026 Sails: Apr 20, More...
Royal Caribbean, Utopia of the Seas
Utopia of the Seas4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Apr 20, More...
American Cruise Lines, American Symphony
American Symphony8 Night - Music Cities Cruise
Starting in Memphis, TN, Day of River Cruising, Cruising the Ohio River, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Dover TN, Clarksville, TN, Nashville, TN
2026 Sails: Apr 21, Jul 14, Sep 8, 2027: Apr 20, Oct 8, More...
American Cruise Lines, American West
American West8 Night - Columbia & Snake Rivers Cruise
Starting in Clarkston, WA, Cruising the Snake River, Pendleton, OR / Richland, WA, Cruising the Columbia River, Hood River, OR, Kalama, WA, Astoria, Or, Day of Cruising, Portland-OR
2026 Sails: Apr 21, May 10, May 24, Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, Oct 11, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy4 Night - Bahamas - Short
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Nassau, Bahamas, Miami, Fl
2026 Sails: Apr 21, Dec 18, 2027: Feb 15, 2028: Jan 3, More...
Quantum of the Seas3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Apr 21, More...

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United States Cruise Departures