United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Carnival Cruise Lines, Carnival Conquest

4 Night - Bahamas
Starting in Miami, Fl, Relaxaway, Half Moon Cay, Celebration Key, the Bahamas, Miami, Fl
2026 Sails: Sep 17, Oct 1, Oct 15, Oct 19, Oct 29, Nov 23, Dec 14, Dec 24, Dec 31, 2027: Feb 22, Mar 1, Mar 29, May 10, May 17, Jun 7, Jun 14, Jun 21, Jul 19, Aug 2, Aug 16, Sep 13, Sep 27, Oct 4, Nov 22, More...

Celebrity Cruises, Celebrity Silhouette

11 Night - Boston, Maine & Canada Cruise
Starting in Boston, Massachusetts, Rockland, Maine, Halifax, Nova Scotia, Sydney NS, Nova Scotia, Quebec City, Quebec, Charlottetown, Prince Edward Island, Portland ME, Boston, Massachusetts
2026 Sails: Sep 17, Sep 28, Oct 9, 2027: Sep 2, Sep 24, More...

Cunard Line, Queen Elizabeth

40 Night - Seattle to Miami
Starting in Seattle, WA, Ketchikan, AK, Juneau, AK, Endicott Arm, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Sep 17, More...

Cunard Line, Queen Elizabeth

7 Night - Alaska Roundtrip from Seattle
Starting in Seattle, WA, Ketchikan, AK, Juneau, AK, Endicott Arm, AK, (Scenic Cruising), Victoria CA, Canada, Seattle, WA
2026 Sails: Sep 17, More...

Norwegian Cruise Line, Norwegian Spirit

12 Night - South Pacific
Starting in Honolulu, Hi, Kahului, Maui, Hi, Kona, Hi, Nawiliwili, Kauai, Hawaii, Bora Bora, French Polynesia, Raiatea, French Polynesia, Moorea, French Polynesia, Papeete, French Polynesia
2026 Sails: Sep 17, More...

Princess Cruises, Ruby Princess

16 Night - Hawaiian Islands
Starting in San Francisco, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Kona, Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Sep 17, More...

Royal Caribbean, Independence of the Seas

9 Night - Canada & New England Cruise
Starting in Cape Liberty, Nj (Ny Metro), Boston, Massachusetts, Portland ME, Halifax, Nova Scotia, Saint John NB (Bay of Fundy), Cape Liberty, Nj (Ny Metro)
2026 Sails: Sep 17, More...

Royal Caribbean, Quantum of the Seas

5 Night - Cabo Overnight Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Sep 17, More...

American Cruise Lines, American Patriot

8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...

American Cruise Lines, American Ranger

8 Night - Hudson River Summer Classic Cruise
Starting in New York, NY, Cruising the Hudson River, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2026 Sails: Sep 18, More...

<= Back

More =>

United States Cruise Departures