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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Carnival Cruise Lines, Carnival Liberty
Carnival Liberty7 Night - Western Caribbean
Starting in New Orleans, La, Mahogany Bay, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Apr 19, More...
Celebrity Cruises, Celebrity Eclipse
Celebrity Eclipse6 Night - Grand Cayman, Mexico & Perfect Day
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Apr 19, More...
Cunard Line, Queen Anne
Queen Anne11 Night - Miami to Southampton
Starting in Miami, FL, Ponta Delgada, Azores, Portugal, Southampton, England, UK
2026 Sails: Apr 19, More...
Disney Cruise Line, Disney Magic
Disney Magic4 Night - Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Apr 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa13 Night - Msc Grand Voyages
Starting in Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal, Barcelona, Spain
2026 Sails: Apr 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa10 Night - Msc Grand Voyages
Starting in Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal
2026 Sails: Apr 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa19 Night - Msc Grand Voyages
Starting in Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal, Barcelona, Spain, Cannes (Cote D Azur), France, Genoa (Portofino), Italy, La Spezia (Cinque Terre), Italy, Civitavecchia (Rome), Italy, Palma De Mallorca (Balearic Islands), Spain
2026 Sails: Apr 19, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa14 Night - Msc Grand Voyages
Starting in Miami, Florida, Philipsburg, St Maarten, Funchal (Madeira Islands), Portugal, Barcelona, Spain, Cannes (Cote D Azur), France
2026 Sails: Apr 19, More...
MSC Cruises, MSC Meraviglia
MSC Meraviglia10 Night - Msc Grand Voyages
Starting in New York City (Brooklyn), New York, Halifax, Canada, Ponta Delgada (Azores), Portugal, Lisbon (Cascais), Portugal
2026 Sails: Apr 19, More...
MSC Cruises, MSC Meraviglia
MSC Meraviglia20 Night - MSC Grand Voyages
Starting in New York City (Brooklyn), New York, Halifax, Canada, Ponta Delgada (Azores), Portugal, Lisbon (Cascais), Portugal, Cadiz (Seville), Spain, Malaga (Granada), Spain, Marseille (Provence), France, Barcelona, Spain, La Goulette, Tunisia, Palermo (Monreale), Italy, Naples (Pompeii), Italy
2026 Sails: Apr 19, More...

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United States Cruise Departures