Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Las Palmas
Starting in Las Palmas (Gran Canaria), Funchal (Madeira), Santa Cruz de Tenerife, Agadir, Arrecife (Lanzarote), Las Palmas (Gran Canaria)
2027 Sails: Mar 5, More...

Windstar, Wind Spirit

4 Night - Quick Getaways : Almeria, Gibraltar & Tangier
Starting in Malaga, Almeria, Granada, Gibraltar, Tangier, Malaga
2027 Sails: Mar 6, Mar 10, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Agadir, Arrecife (Lanzarote), Las Palmas (Gran Canaria), Port Rosario (Fuerteventura), Santa Cruz de Tenerife
2027 Sails: Mar 7, Mar 21, More...

Costa Cruise Lines, Costa Smeralda

Viking Ocean, Viking Star

14 Night - Gems of the Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Salerno, Palermo, Sicily, Tunis (La Goulette), Sardinia (Cagliari), Sail the Mediterranean Sea, Valencia, Barcelona
2027 Sails: Mar 9, More...

Azamara Cruises, Azamara Onward

Deal link -> Special

12 Night - Best of the Mediterranean Cruise : Monte Carlo, Florence, Rome & Venice
Starting in Barcelona, Provence (Marseille), Nice, Florence / Pisa (Livorno), Rome (Civitavecchia), Amalfi Coast (Salerno), Siracusa, Sicily, Kotor, Dubrovnik, Croatia, Zadar, Venice (Fusina)
2027 Sails: Mar 13, More...

Azamara Cruises, Azamara Onward

Deal link -> Special

21 Night - Mediterranean Combination Cruise : Florence, Dubrovnik & Athens
Starting in Barcelona, Provence (Marseille), Nice, Florence / Pisa (Livorno), Rome (Civitavecchia), Amalfi Coast (Salerno), Siracusa, Sicily, Kotor, Dubrovnik, Croatia, Zadar, Venice (Fusina), Koper, Zadar, Split, Dubrovnik, Croatia, Kotor, Chania (Souda), Crete, Athens (Piraeus)
2027 Sails: Mar 13, More...

AmaWaterways Tours, AmaDolce Tours

14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Paris
2027 Sails: Mar 14, Mar 21, Mar 28, Apr 4, Jul 4, Jul 11, Jul 18, Aug 1, Aug 8, Aug 15, Sep 26, Nov 21, Nov 28, Dec 5, Dec 12, More...

AmaWaterways Tours, AmaDolce Tours

14 Night - Taste of Bordeaux (Wine Cruise) with Bilbao, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Bilbao, San Sebastian, Bordeaux, Libourne, Blaye, Engelhartszell, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Amboise, Paris
2027 Sails: Mar 14, Mar 21, Mar 28, Apr 4, Jul 4, Jul 11, Jul 18, Aug 1, Aug 8, Aug 15, Sep 26, Nov 21, Nov 28, Dec 5, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Funchal (Madeira), Las Palmas (Gran Canaria), Port Rosario (Fuerteventura), Santa Cruz de Tenerife
2027 Sails: Mar 14, More...

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