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Madrid Cruise Departures

Cruises that depart from Europe: Spain: Madrid

Cruises that visit Madrid

See all River Cruises that depart from Madrid

Click on a cruise ship itinerary sailing from Madrid (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Madrid), please visit: Cruise Search or try our Virtual Cruise Advisor™.


AmaVida Cruises13 Night - Flavors of Portugal & Spain : 7-Night Cruise with 3 Nights Pre-Cruise and 3 Nights Post-Cruise : Madrid to Lisbon : ms AmaVida
Starting in Madrid with stops in Toledo, Vega Terron, Pinhao, Regua, Entre-os-Rios, Porto, Lisbon, Sintra
2021 Sails: Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, Oct 30, More...
ms Andorinha Cruises12 Night - Exploring the Douro, plus Lisbon & Madrid - Westbound Aboard ms Andorinha
Starting in Madrid with stops in Salamanca, Castelo Rodrigo, Pinhao, Peso da Regua, Guimaraes, Porto, Lisbon
2021 Sails: Apr 29, May 20, Jun 10, Aug 5, Oct 28, Nov 11, More...
Emerald Waterways Ships Cruises9 Night - Madrid and Secrets of the Douro from Madrid to Porto
Starting in Madrid; with stops in Porto; Pinhao; Vega de Terron; Salamanca; Pocinho; Regua; Porto
2021 Sails: May 13, May 27, Jun 10, Jul 8, Aug 5, Sep 30, Oct 28, More...
Enchanted Princess Cruise Tours13 Night - Highlights of Spain - Tour 2A From Madrid, Spain to Rome (Civitavecchia), Italy
Land first (6 days), followed by cruise (7 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 4 Ports: Rome (Civitavecchia), Italy; Corsica (Ajaccio), France; Gibraltar; Marseille (Provence), France; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy
2021 Sails: May 23, Jul 4, Jul 25, Aug 15, More...
Enchanted Princess Cruise Tours13 Night - Highlights of Spain - Tour 2A From Madrid, Spain to Rome (Civitavecchia), Italy
Land first (6 days), followed by cruise (7 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 5 Ports: Rome (Civitavecchia), Italy; Kotor, Montenegro; Corfu, Greece; Katakolon (Olympia), Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy
2021 Sails: Jun 13, Sep 5, More...
Enchanted Princess Cruise Tours17 Night - Highlights of Spain - Tour 2D From Madrid, Spain to Rome (Civitavecchia), Italy
Land Tour: Madrid, Spain; Valencia, Spain; Barcelona, Spain Cruise Ports: Barcelona, Spain; Marseille (Provence), France; Florence/Pisa (Livorno), Italy; Valletta, Malta; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy
2021 Sails: Sep 26, Oct 18, More...
Enchanted Princess Cruise Tours28 Night - Highlights of Spain - Tour 2E From Madrid, Spain to Barcelona, Spain
Land first (6 days), followed by cruise (22 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 15 Ports: Barcelona, Spain; Marseille (Provence), France; Florence/Pisa (Livorno), Italy; Valletta, Malta; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy; Athens (Piraeus), Greece; Kusadasi, Turkey (for Ephesus); Santorini, Greece; Mykonos, Greece; Katakolon (Olympia), Greece; Corsica (Ajaccio), France; Toulon/Provence (La Seyne), France; Barcelona, Spain
2021 Sails: Sep 26, More...
Enchanted Princess Cruise Tours28 Night - Highlights of Spain - Tour 2G From Madrid, Spain to Barcelona, Spain
Land first (6 days), followed by cruise (22 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain; 15 Ports: Barcelona, Spain; Marseille (Provence), France; Florence/Pisa (Livorno), Italy; Valletta, Malta; Kotor, Montenegro; Corfu, Greece; Sicily (Messina), Italy; Naples, Italy (for Capri & Pompeii); Rome (Civitavecchia), Italy; Kotor, Montenegro; Dubrovnik, Croatia; Athens (Piraeus), Greece; Mykonos, Greece; Katakolon (Olympia), Greece; Corsica (Ajaccio), France; Toulon/Provence (La Seyne), France; Barcelona, Spain
2021 Sails: Oct 18, More...
Discovery Princess Cruise Tours13 Night - Highlights of Spain Tour 2A from Madrid, Spain to Rome (Civitavecchia), Italy
Land first (6 days), followed by cruise (7 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain 4 Ports: Barcelona, Spain; Gibraltar; Corsica (Ajaccio), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy
2021 Sails: Nov 11, More...
Discovery Princess Cruise Tours27 Night - Highlights of Spain Tour 2F from Madrid, Spain to Ft. Lauderdale, Florida
Land first (6 days), followed by cruise (21 days) 3 Land Destinations: Madrid, Spain; Valencia, Spain; Barcelona, Spain 9 Ports: Barcelona, Spain; Gibraltar; Corsica (Ajaccio), France; Genoa, Italy; Florence/Pisa (Livorno), Italy; Rome (Civitavecchia), Italy; Corsica (Ajaccio), France; Barcelona, Spain; Seville (Cadiz), Spain; Santa Cruz De Tenerife, Spain; Ft. Lauderdale, Florida
2021 Sails: Nov 11, More...


Madrid Cruise Departures

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