Madrid Cruise Departures
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-Cruise
Starting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, More...
13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Aug 23, More...
12 Night - Yachtsman's Mediterranean Rivieras & Madrid Cruise Tour
Starting in Madrid, Spain, Barcelona, Palamos, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Porto Ercole, Rome
2026 Sails: Sep 7, More...13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Sep 13, More...
10 Night - Madrid & Secrets of the Douro
Starting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto
2026 Sails: Sep 23, More...13 Night - Madrid to Lisbon & Secrets of the Douro
Starting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto, Porto / Lisbon, Lisbon
2026 Sails: Sep 23, More...13 Night - Highlights of Spain - Tour 2A
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Oct 4, More...
14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Paris Post Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Paris
2026 Sails: Oct 25, Nov 1, More...14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-Cruise
Starting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, More...21 Night - Highlights of Spain - Tour 2D
Starting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
Cruises that depart from Europe: Spain: Madrid
Cruises that visit Madrid
See all River Cruises that depart from Madrid
Click on a cruise ship itinerary sailing from Madrid (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Madrid), please visit: Cruise Search or try our Virtual Cruise Advisor™.
13 Night - Flavors of Portugal & Spain with Madrid Pre-Cruise and Lisbon Post-CruiseStarting in Madrid, Salamanca, Vega de Terron, Pinhao, El Dorado, Porto, Lisbon
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, Sep 23, Oct 7, More...
13 Night - Highlights of Spain - Tour 2AStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Aug 23, More...
12 Night - Yachtsman's Mediterranean Rivieras & Madrid Cruise TourStarting in Madrid, Spain, Barcelona, Palamos, Sanary-sur-mer, Monte Carlo, Cannes, Portofino, Portoferraio, Porto Ercole, Rome
2026 Sails: Sep 7, More...
13 Night - Highlights of Spain - Tour 2AStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Corsica (Ajaccio), France, Marseille (Provence), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Sep 13, More...
10 Night - Madrid & Secrets of the DouroStarting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto
2026 Sails: Sep 23, More...
13 Night - Madrid to Lisbon & Secrets of the DouroStarting in Madrid, Madrid / Porto, Porto / Pinhao, Pinhao / Vega de Terron, Vega de Terron / Salamanca, Pocinho / Regua, Regua, Porto, Porto / Lisbon, Lisbon
2026 Sails: Sep 23, More...
13 Night - Highlights of Spain - Tour 2AStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Ibiza, Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Oct 4, More...
14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Paris Post CruiseStarting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Paris
2026 Sails: Oct 25, Nov 1, More...
14 Night - Taste of Bordeaux (Wine Cruise) with Madrid, San Sebastian Pre-Cruise and Loire Valley, Paris Charles De Gaulle Post-CruiseStarting in Madrid, San Sebastian, Bordeaux, Libourne, Blaye, Bourg, Cussac-Fort-Medoc, Cadillac, Bordeaux, Loire Valley / Amboise, Aboisso, Paris
2026 Sails: Oct 25, Nov 1, More...
21 Night - Highlights of Spain - Tour 2DStarting in Madrid, Spain, Valencia, Spain, Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 25, More...
