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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Cartagena ES : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Oceania Cruises, Oceania Allura
Oceania Allura32 Night - Rivieras to the Caribbean
Starting in Barcelona (Tarragona), Palamos, Sete, Provence (Marseille), Savona, Cinque Terre (La Spezia), Portoferraio (Elba), Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Trapani (Sicily), Tunis (La Goulette), Cagliari (Sardinia), Cartagena ES, Valencia, Barcelona, Malaga, Agadir, Arrecife (Lanzarote), San Juan, Miami
2026 Sails: Oct 31, More...
Oceania Cruises, Oceania Allura
Oceania Allura17 Night - Grand Mediterranean Jewels
Starting in Barcelona (Tarragona), Palamos, Sete, Provence (Marseille), Savona, Cinque Terre (La Spezia), Portoferraio (Elba), Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Trapani (Sicily), Tunis (La Goulette), Cagliari (Sardinia), Cartagena ES, Valencia, Barcelona
2026 Sails: Oct 31, More...
Oceania Cruises, Oceania Allura
Oceania Allura7 Night - Luminous Mediterranean
Starting in Barcelona (Tarragona), Palamos, Sete, Provence (Marseille), Savona, Cinque Terre (La Spezia), Portoferraio (Elba), Rome (Civitavecchia)
2026 Sails: Oct 31, More...
Princess Cruises, Sun Princess
Sun Princess15 Night - Western Europe Passage
Starting in Barcelona, Spain, Malaga, Spain, Gibraltar, Seville (Cadiz), Spain, Santa Cruz de Tenerife, Fort Lauderdale, Florida
2026 Sails: Oct 31, More...
Royal Caribbean, Explorer of the Seas
Explorer of the Seas13 Night - Spain, & Bermuda Transatlantic
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Cartagena ES, Ponta Delgada, Azores, Royal Naval Dockyard, Bermuda, Orlando (Port Canaveral), Fl
2026 Sails: Oct 31, More...
Viking Ocean, Viking Saturn
Viking Saturn14 Night - Mediterranean Antiquities
Starting in Barcelona (Tarragona), Sete, Marseille, Monte Carlo, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Oct 31, More...
Windstar, Wind Star
Wind Star10 Night - Treasures of Southern Spain & Morocco
Starting in Barcelona, Tarragona, Spain, Palma De Mallorca, Valencia, Cartagena ES, Malaga, Tangier, Lisbon
2026 Sails: Oct 31, More...
EXPLORA I24 Night - A Grand Journey of Vibrant Cultures, Mayan Marvels & Idyllic Beaches
Starting in Barcelona, Cadiz, Funchal (Madeira), St Johns AG, Antigua, Road Bay, San Juan, Miami, Merida (Progreso), Roatan Island, Belize City, Ocean Cay, Miami
2026 Sails: Nov 1, More...
EXPLORA I16 Night - A Grand Journey of Lively Culture & Stunning Beaches
Starting in Barcelona, Cadiz, Funchal (Madeira), St Johns AG, Antigua, Road Bay, San Juan, Miami
2026 Sails: Nov 1, More...
MSC Cruises, MSC Sinfonia
MSC Sinfonia7 Night - Mediterranean
Starting in Tarragona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy, Livorno (Florence), Italy, Valencia, Spain, Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain
2026 Sails: Nov 1, More...

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Spain Cruise Departures