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Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Ibiza : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Departing from
Spain
Cruise Specials

Norwegian Line Tours, Norwegian Sky Tours
Norwegian Sky Tours12 Night - Explore Barcelona Pre Cruisetour
Starting in At Hotel, Barcelona, Spain, Nice / Monaco (Villefranche), France, Livorno / Florence / Pisa, Italy, Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Santorini Island, Greece, Mykonos, Greece, Heraklion / Crete, Greece, Piraeus / Athens, Greece
2026 Sails: Aug 28, More...
Silversea, Silver Muse
Silver Muse9 Night - Barcelona to Barcelona
Starting in Barcelona, Marseille, Monte Carlo, Porto Mahon, Palma De Mallorca, Ibiza, Alicante, Valencia, Barcelona
2026 Sails: Aug 29, More...
Oceania Nautica14 Night - Iberia Celebration
Starting in Bilbao, La Coruna, Santiago De Compostela (Vigo), Lisbon, Portimao, Seville, Seville (Cadiz), Alicante, Barcelona, Mahon (Menorca), Saint-Tropez, Florence / Pisa / Tuscany (Livorno), Rome (Civitavecchia)
2026 Sails: Aug 30, More...
Royal Caribbean, Legend of the Seas
Legend of the Seas7 Night - Western Mediterranean Cruise
Starting in Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain
2026 Sails: Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, More...
Explora Journeys, EXPLORA I
EXPLORA I14 Night - An Extended Journey Through Timeless Coastal Beauty & Cultural Splendour
Starting in Barcelona, Ibiza, Tunis / La Goulette, La Valletta, Giardini Naxos, Sorrento, Civitavecchia (Rome), Porto Santo Stefano (Argentario), Monte Carlo, Cannes, Valencia, Palma De Mallorca, Barcelona
2026 Sails: Aug 31, More...
Norwegian Cruise Line, Norwegian Sky
Norwegian Sky9 Night - Greek Isles, Italy, & France : European Jewels
Starting in Barcelona, Spain, Nice / Monaco (Villefranche), France, Livorno / Florence / Pisa, Italy, Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Santorini Island, Greece, Mykonos, Greece, Heraklion / Crete, Greece, Piraeus / Athens, Greece
2026 Sails: Aug 31, More...
Regent Seven Seas, Seven Seas Navigator
Seven Seas Navigator10 Night - Extravagant Ionian Journey
Starting in Barcelona, Cruising the Ionian Sea, Tuscany (Livorno), Rome (Civitavecchia), Naples / Pompeii, Valletta, Cruising the Ionian Sea, Dubrovnik, Croatia, Split, Koper, Venice (Fusina)
2026 Sails: Sep 2, More...
Celebrity Cruises, Celebrity Equinox
Celebrity Equinox9 Night - Spain, Portugal & Morocco
Starting in Barcelona, Spain, Seville (Cadiz), Spain, Porto (Leixoes), Portugal, Lisbon, Portugal, Tangier, Morocco, Barcelona, Spain
2026 Sails: Sep 3, More...
Norwegian Line Tours, Norwegian Epic Tours
Norwegian Epic Tours10 Night - Explore Barcelona Pre Cruisetour
Starting in At Hotel, Barcelona, Spain, Provence, Marseille, France, Cannes, France, Livorno / Florence / Pisa, Italy, Messina, Italy, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy
2026 Sails: Sep 3, More...
Silversea, Silver Shadow
Silver Shadow5 Night - Malaga to Lisbon
Starting in Malaga (Costa del Sol), Gibraltar, Sevilla, Lisbon
2026 Sails: Sep 4, More...

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Spain Cruise Departures