Spain Cruise Departures

Cruises that depart from Europe: Spain

Cruises that visit Spain

See all River Cruises that depart from Spain

Click on a cruise ship itinerary sailing from Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alicante : Barcelona : Bilbao : Cadiz : Canary Islands : Madrid : Malaga : Palma de Majorca : Seville : Tarragona : Valencia : Vega de Terron

Explora Journeys, EXPLORA II

11 Night - A Journey from Ligurian Shores to the Cyclades' Dazzling Beauty
Starting in Barcelona, La Spezia, Civitavecchia (Rome), Port of Naples, Siracusa (Sicily), La Valletta, Mykonos, Patmos, Santorini, Piraeus (Athens)
2027 Sails: Mar 14, More...

Explora Journeys, EXPLORA II

Deal link -> Special

6 Night - A Journey of Layers, Light and Living History
Starting in Barcelona, La Spezia, Civitavecchia (Rome), Port of Naples, Siracusa (Sicily), La Valletta
2027 Sails: Mar 14, More...

Windstar, Wind Spirit

15 Night - Star Collector : Iberian Soul & Italian Style
Starting in Malaga, Tangier, Cartagena ES, Valencia, Palma De Mallorca, Tarragona (Barcelona), Barcelona, Nice, Genoa, Livorno, Civitavecchia, Rome
2027 Sails: Mar 14, More...

Windstar, Wind Spirit

8 Night - Treasures of Southern Spain & Morocco
Starting in Malaga, Tangier, Cartagena ES, Valencia, Palma De Mallorca, Tarragona (Barcelona), Barcelona
2027 Sails: Mar 14, 2028: Mar 18, More...

Celebrity Cruises, Celebrity Infinity

7 Night - Italy, Greece & Malta Cruise
Starting in Barcelona, Spain, Valletta, Malta, Sicily (Messina), Italy, Heraklion (Iraklion), Crete, Nafplio, Greece, Athens (Piraeus), Greece
2027 Sails: Mar 15, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from S. Cruz De Tenerife
Starting in Santa Cruz de Tenerife, Arrecife (Lanzarote), Funchal (Madeira), Las Palmas (Gran Canaria), Port Rosario (Fuerteventura), Santa Cruz de Tenerife
2027 Sails: Mar 15, More...

Costa Cruise Lines, Costa Favolosa

4 Night - Southern Europe Roundtrip from Barcelona
Starting in Barcelona, Marseille, Savona, Barcelona
2027 Sails: Mar 19, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Las Palmas (Gran Canaria)
Starting in Las Palmas (Gran Canaria), Port Rosario (Fuerteventura), Santa Cruz de Tenerife, Agadir, Arrecife (Lanzarote), Las Palmas (Gran Canaria)
2027 Sails: Mar 19, More...

Viking Ocean, Viking Sea

7 Night - Iconic Western Mediterranean
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia)
2027 Sails: Mar 19, More...

Viking Ocean, Viking Sea

14 Night - Mediterranean & Italian Sojourn
Starting in Barcelona, Sete, Marseille, Villefranche-Sur-Mer, Florence / Pisa (Livorno), Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2027 Sails: Mar 19, More...

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