Spain Cruises

Cruises that visit Europe: Spain

Cruises that depart from Spain

See all River Cruises that visit Spain

Click on a cruise ship itinerary that visits Spain (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Spain), please visit: Cruise Search or try our Virtual Cruise Advisor™.

AmaWaterways, AmaSintra

7 Night - Enticing Douro
Starting in Porto, Regua, Vega de Terron, Pinhao, Regua, Porto
2026 Sails: May 29, Jun 12, Jul 3, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Oct 2, Nov 20, 2027: Mar 19, Mar 26, Apr 2, Apr 30, May 7, May 21, May 28, Jun 4, Jun 11, Jun 18, Jun 25, More...

Celebrity Cruises, Celebrity Apex

8 Night - Spain and Portugal Cruise
Starting in Southampton, England, Vigo, Spain, Lisbon, Portugal, Porto (Leixoes), Portugal, La Coruna, Spain, Bilbao, Southampton, England
2026 Sails: May 29, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Civitavecchia
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome)
2026 Sails: May 29, More...

Costa Cruise Lines, Costa Toscana

7 Night - Western Mediterranean from Genova
Starting in Genoa (Portofino), Marseille, Barcelona, Cagliari, Napoli, Civitavecchia (Rome), Genoa (Portofino)
2026 Sails: May 29, Jul 24, Jul 31, Aug 7, More...

MSC Cruises, MSC Grandiosa

7 Night - Mediterranean
Starting in Palma De Mallorca (Balearic Islands), Spain, Barcelona, Spain, Cannes (Cote D Azur), France, Genoa (Portofino), Italy, La Spezia (Cinque Terre), Italy, Civitavecchia (Rome), Italy, Palma De Mallorca (Balearic Islands), Spain
2026 Sails: May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, More...

MSC Cruises, MSC Meraviglia

7 Night - Mediterranean
Starting in Palermo (Monreale), Italy, Naples (Pompeii), Italy, Livorno (Florence), Italy, Marseille (Provence), France, Barcelona, Spain, La Goulette, Tunisia, Palermo (Monreale), Italy
2026 Sails: May 29, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, More...

MSC Cruises, MSC Orchestra

7 Night - Mediterranean
Starting in Tarragona, Spain, Valencia, Spain, Livorno (Florence), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Tarragona, Spain
2026 Sails: May 29, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, More...

MSC Cruises, MSC Seaview

7 Night - Mediterranean
Starting in Marseille (Provence), France, Genoa (Portofino), Italy, Civitavecchia (Rome), Italy, Palermo (Monreale), Italy, Ibiza (Balearic Islands), Spain, Barcelona, Spain, Marseille (Provence), France
2026 Sails: May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, More...

MSC Cruises, MSC Splendida

7 Night - Mediterranean
Starting in La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Livorno (Florence), Italy, Cagliari (Sardinia), Italy, Palermo (Monreale), Italy, La Valletta, Malta
2026 Sails: May 29, Jun 5, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, Jul 24, Jul 31, Aug 7, Aug 14, Aug 21, Aug 28, Sep 4, Sep 11, Sep 18, Sep 25, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, Nov 6, More...

AmaWaterways Tours, AmaDouro Tours

10 Night - Enticing Douro with Lisbon Pre-Cruise
Starting in Lisbon, Porto, Vega de Terron, Pinhao, Porto
2026 Sails: May 30, Jun 27, Jul 11, Jul 18, Jul 25, Aug 15, Aug 22, Sep 5, Sep 26, 2027: Apr 10, Apr 24, May 1, May 8, May 15, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 24, Aug 7, Aug 21, Aug 28, Sep 4, More...

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