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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



HAL Zuiderdam Cruise Ship18 Night - Circle Hawaii
Starting in San Diego with stops in Hilo, Kona, Honolulu, Nawiliwili, Lahaina, Ensenada
2021 Sails: Dec 5, More...
HAL Koningsdam Cruises7 Night - Mexican Riviera
Starting in San Diego with stops in Puerto Vallarta, Mazatlan, Cabo San Lucas
2021 Sails: Dec 19, Dec 26, More...
HAL Zuiderdam Cruise Ship10 Night - Mexican Sea Of Cortez Holiday
Starting in San Diego with stops in Cabo San Lucas, Pichilingue, Loreto, Guaymas, Topolobampo, Mazatlan
2021 Sails: Dec 23, More...
HAL Zuiderdam Cruise Ship14 Night - Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena, Fort Lauderdale
2022 Sails: Jan 2, Jan 30, More...
HAL Koningsdam Cruises24 Night - Mexican Riviera & Circle Hawaii Collector
Starting in San Diego with stops in Puerto Vallarta, Mazatlan, Cabo San Lucas, Honolulu, Nawiliwili, Lahaina, Kona, Hilo, Ensenada
2022 Sails: Jan 9, More...
HAL Koningsdam Cruises17 Night - Circle Hawaii
Starting in San Diego with stops in Honolulu, Nawiliwili, Lahaina, Kona, Hilo, Ensenada
2022 Sails: Jan 16, More...
Seven Seas Explorer Cruises16 Night - San Diego California to Miami Florida on Seven Seas Explorer
Starting in San Diego with stops in Catalina Island, Cruising the Pacific Ocean, Cabo San Lucas, Acapulco, Puerto Quetzal, Corinto, Puntarenas, Panama Canal Transit, Cartagena, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2022 Sails: Jan 19, More...
HAL Koningsdam Cruises18 Night - Circle Hawaii
Starting in San Diego with stops in Nawiliwili, Honolulu, Lahaina, Hilo, Kona, Ensenada
2022 Sails: Feb 2, More...
HAL Koningsdam Cruises25 Night - Circle Hawaii & Mexican Riviera Collector
Starting in San Diego with stops in Nawiliwili, Honolulu, Lahaina, Hilo, Kona, Ensenada, Puerto Vallarta, Mazatlan, Cabo San Lucas
2022 Sails: Feb 2, More...
HAL Zuiderdam Cruise Ship35 Night - Hawaii, Tahiti & Marquesa
Starting in San Diego with stops in Hilo, Honolulu, Lahaina, Cross International Dateline, Kiritimati, Crossing the Equator, Bora Bora, Raiatea, Papeete, Moorea, Maroe Bay, Avatoru, Fakarava, Taiohae
2022 Sails: Feb 27, More...


San Diego Cruise Departures

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