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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor.


Holland America Line (HAL), HAL Nieuw Amsterdam Deal link -> Discount special
HAL Nieuw Amsterdam Cruise Ship18 Night Panama Canal
18 Nights - Starting in San Diego with stops in Puerto Vallarta, Manzanillo, Huatulco, Puerto Chiapas, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Half Moon Cay, Fort Lauderdale
2018 Sails: Oct 3, More...
 
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship7 Night Mexican Riviera Cruise roundtrip from San Diego, CA
7 Nights - Starting in San Diego, CA; with stops in Puerto Vallarta, Mexico; Mazatlán, Mexico; Cabo San Lucas, Mexico; San Diego, CA
2018 Sails: Oct 7, More...
 
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship7 Night Mexican Riviera Cruise roundtrip from San Diego, California
7 Nights - Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Mazatlán, Mexico; Puerto Vallarta, Mexico; San Diego, California
2018 Sails: Oct 7, More...
 
Celebrity Cruises, Celebrity Infinity
Celebrity Infinity Cruise Ship15 Nights Eastbound Panama Canal Cruise on Celebrity Infinity
15 Nights - Starting in San Diego with stops in Cabo San Lucas, Puerto Vallarta, Puerto Quetzal, Puntarenas, Panama Canal (Cruising), Colon, Cartagena, Fort Lauderdale
2018 Sails: Oct 9, More...
 
PONANT, Le Soleal Deal link -> Discount special
Le Soleal Cruises13 Night The Sea of Cortez from San Diego to Puerto Quetzal
13 Nights - Starting in San Diego; with stops in Cabo San Lucas; Coronado Island; Danzante Island; Monserrat Island; Puerto Agua Verde; Punta Colorada, Isla San Jose; Bahia Amortajada, Isla San Jose; Los Islotes; Isla Partida; Espíritu Santo Island; Cerralvo Island; Huatulco; Puerto Quetzal
2018 Sails: Oct 9, More...
 
Disney Cruise Line, Disney Wonder
Disney Wonder Cruise Ship14 Night Eastbound Panama Canal Cruise from San Diego, CA to Galveston, TX
14 Nights - Starting in San Diego, CA; with stops in Cabo San Lucas, Mexico; Puerto Vallarta, Mexico; Panama Canal; Cartagena, Colombia; Cozumel, Mexico; Galveston, TX
2018 Sails: Oct 19, More...
 
Holland America Line (HAL), HAL Eurodam Deal link -> Discount special
HAL Eurodam Cruise Ship7 Night Mexican Riviera
7 Nights - Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2018 Sails: Oct 21, Nov 4, Dec 9, Dec 16, 2019: Jan 6, Jan 13, Jan 20, Jan 27, Apr 6, More...
 
Norwegian Cruise Line (NCL), NCL Norwegian Pearl Deal link -> Adventure special
NCL Norwegian Pearl Cruise Ship14 Night Panama Canal from San Diego
14 Nights - Starting in San Diego with stops in Cabo San Lucas, Puerto Quetzal, San Juan del Sur, Puntarenas, Daylight Transit Panama Canal, Cartagena, George Town, Tampa
2018 Sails: Oct 21, More...
 
Holland America Line (HAL), HAL Volendam
HAL Volendam Cruise Ship15 Night Panama Canal
15 Nights - Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena, Half Moon Cay, Fort Lauderdale
2018 Sails: Nov 3, 2019: Jan 3, Apr 3, More...
 
Holland America Line (HAL), HAL Eurodam Deal link -> Discount special
HAL Eurodam Cruise Ship18 Night Circle Hawaii
18 Nights - Starting in San Diego with stops in Kona, Scenic cruising Kilauea Volcano, Hilo, Honolulu, Nawiliwili, Lahaina, Ensenada
2018 Sails: Nov 11, More...
 
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San Diego Cruise Departures

 
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