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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Disney Wonder Cruise Ship7 Night - Mexican Riviera Cruise from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Mazatlán, Mexico; Puerto Vallarta, Mexico; San Diego, California
2021 Sails: Apr 11, Oct 1, More...
HAL Koningsdam Cruises7 Night - Classic California Coast
Starting in San Diego with stops in Santa Barbara, Los Angeles, Monterey, San Francisco, Ensenada
2021 Sails: Apr 17, More...
Disney Wonder Cruise Ship3 Night - Baja Cruise from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; and San Diego, California
2021 Sails: Apr 23, Apr 30, Oct 8, Oct 15, More...
HAL Koningsdam Cruises7 Night - Wine Country & Pacific Northwest
Starting in San Diego with stops in Avalon, Santa Barbara, San Francisco, Victoria, Vancouver
2021 Sails: Apr 24, More...
Disney Wonder Cruise Ship5 Night - Pacific Coast Cruise from San Diego to Vancouver
Starting in San Diego, California; with stops in San Francisco, California; Victoria, Canada; Vancouver, Canada
2021 Sails: May 12, 2022: Apr 21, More...
Carnival Miracle Cruise Ship5 Night - Baja Mexico From San Diego, CA
Starting in San Diego with stops in Cabo San Lucas
2021 Sails: Oct 3, 2022: Oct 1, More...
Star Breeze Cruises7 Night - San Diego to San Diego - Star Breeze
Starting in San Diego with stops in Ensenada, San Francisco, Monterey, Santa Barbara, Catalina Island
2021 Sails: Oct 3, More...
Star Breeze Cruises17 Night - San Diego to Puerto Vallarta - Star Breeze
Starting in San Diego with stops in Ensenada, San Francisco, Monterey, Santa Barbara, Catalina Island, Cabo San Lucas, La Paz, Loreto, Mazatlan, Puerto Vallarta
2021 Sails: Oct 3, More...
HAL Eurodam Cruise Ship17 Night - Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Willemstad, Half Moon Cay, Fort Lauderdale
2021 Sails: Oct 7, More...
Carnival Miracle Cruise Ship3 Night - Baja Mexico From San Diego, CA
Starting in San Diego with stops in Ensenada
2021 Sails: Oct 8, Nov 5, Dec 17, 2022: Jan 28, 2023: Jan 4, More...


San Diego Cruise Departures

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