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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.




Crystal Symphony Cruise Ship32 Night - OCS200113-32 - Pacific Isles & Vietnam Odyssey
Starting in San Diego with stops in Cruising the North Pacific, Honolulu, Lahaina, Nawiliwili, Crossing Dateline- Gain 1 day, Majuro, Cruising the Pacific Ocean, Pohnpei, Guam, Saipan, Manila, Cruising the South China Sea, Da Nang, Hanoi/Hongai, Cruising the Hainan Strait, Hong Kong
2020 Sails: Jan 13, More...
Crystal Symphony Cruise Ship47 Night - OCS200113-47 - Pacific Isles & Asian Temples
Starting in San Diego with stops in Cruising the North Pacific, Honolulu, Lahaina, Nawiliwili, Crossing Dateline- Gain 1 day, Majuro, Cruising the Pacific Ocean, Pohnpei, Guam, Saipan, Manila, Cruising the South China Sea, Da Nang, Hanoi/Hongai, Cruising the Hainan Strait, Hong Kong, Cruising the Coast of Vietnam, Ho Chi Minh City, Koh Samui, Sihanoukville, Singapore
2020 Sails: Jan 13, More...
Carnival Miracle Cruise ShipCarnival Journeys - 15 Night Hawaii From San Diego, CA
Starting in San Diego with stops in Kahului, Honolulu, Nawiliwili, Hilo, Ensenada
2020 Sails: Jan 17, More...
HAL Oosterdam Cruise Ship18 Night Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Manzanillo, Huatulco, Puerto Chiapas, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Half Moon Cay, Fort Lauderdale
2020 Sails: Jan 18, More...
HAL Rotterdam Cruise Ship16 Night Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Willemstad, Half Moon Cay, Fort Lauderdale
2020 Sails: Feb 8, More...
HAL Eurodam Cruise Ship17 Night Circle Hawaii
Starting in San Diego with stops in Kona, Honolulu, Lahaina, Hilo, Scenic cruising Kilauea Volcano, Ensenada
2020 Sails: Mar 1, More...
Seven Seas Splendor Cruises16 Night - San Diego California to Miami Florida on Seven Seas Splendor
Starting in San Diego with stops in Catalina Island, Cruising the Pacific Ocean, Cabo San Lucas, Acapulco, Puerto Quetzal, Corinto, Puntarenas, Panama Canal Daylight Transit, Cartagena, Cruising the Caribbean Sea, George Town, Cruising the Florida Straits, Miami
2020 Sails: Mar 14, More...
HAL Eurodam Cruise Ship18 Night Circle Hawaii
Starting in San Diego with stops in Honolulu, Hilo, Lahaina, Nawiliwili, Kona, Scenic cruising Kilauea Volcano, Ensenada
2020 Sails: Mar 18, More...
Disney Wonder Cruise Ship5-Night Baja Cruise from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2020 Sails: Mar 20, Apr 5, Apr 19, Sep 18, Nov 1, 2021: Mar 19, Mar 28, Apr 2, Apr 18, May 7, More...
HAL Oosterdam Cruise Ship28 Night Hawaii, Tahiti & Marquesas
Starting in San Diego with stops in Hilo, Honolulu, Lahaina, Cross International Dateline, Kiritimati, Crossing the Equator, Bora Bora, Raiatea, Papeete, Moorea, Fakarava, Taiohae
2020 Sails: Mar 21, More...


San Diego Cruise Departures

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