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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Holland America, Koningsdam
Koningsdam11 Night - Mexican Riviera & Sea of Cortez
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Puerto Vallarta, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, San Diego, California
2027 Sails: Dec 7, More...
Holland America, Koningsdam
Koningsdam12 Night - Mexican Riviera Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Ensenada, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Dec 18, More...
Holland America, Koningsdam
Koningsdam5 Night - Mexico Sunshine Getaway
Starting in San Diego, California, Cabo San Lucas, Mexico, Ensenada, Mexico, San Diego, California
2027 Sails: Dec 18, More...
Holland America, Zaandam
Zaandam15 Night - Panama Canal Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Manzanillo, Mexico, Huatulco, Mexico, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Miami, Florida
2027 Sails: Dec 18, More...
Holland America, Koningsdam
Koningsdam16 Night - Mexican Riviera Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Acapulco, Guerrero, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Dec 23, More...
Holland America, Koningsdam
Koningsdam7 Night - Mexican Riviera Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Dec 23, More...
Holland America, Koningsdam
Koningsdam16 Night - Mexican Riviera Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Acapulco, Guerrero, Mexico, Cabo San Lucas, Mexico, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Dec 30, More...
Holland America, Koningsdam
Koningsdam9 Night - Mexican Riviera Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Acapulco, Guerrero, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Dec 30, More...
Holland America, Koningsdam
Koningsdam24 Night - Mexican Riviera & Circle Hawaii
Starting in San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California, Hilo, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2028 Sails: Jan 8, More...
Holland America, Koningsdam
Koningsdam17 Night - Circle Hawaii
Starting in San Diego, California, Hilo, Hawaii, Kahului, Maui, Nawiliwili, Kauai, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Diego, California
2028 Sails: Jan 15, More...

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San Diego Cruise Departures