San Diego Cruise Departures
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
7 Night - Mexican Riviera
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 7, More...
15 Night - Panama Canal Eastward Cruise
Starting in San Diego, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, George Town, Grand Cayman, Tampa, Florida
2027 Sails: Oct 7, More...
36 Night - Inca Coast Discovery Collectors' Voyage
Starting in San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Daylight cruising Glacier Alley, Ushuaia, Argentina, Scenic Cruising Cape Horn, Port Stanley, Falkland Islands, Montevideo, Uruguay, Buenos Aires, Argentina
2027 Sails: Oct 12, More...21 Night - Inca Coast Discovery Segment
Starting in San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile
2027 Sails: Oct 12, More...35 Night - Hawaii, Tahiti & Marquesas Legendary Voyage
Starting in San Diego, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Maui, Kona, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Avatoru, Rangiroa, French Polynesia, Huahine, French Polynesia, Bora Bora, French Polynesia, Raiatea, Society Islands, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Papeete, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Oct 14, More...
7 Night - Baja Peninsula
Starting in San Diego, California, Loreto, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 23, More...14 Night - Baja Peninsula & Classic California Coast
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California
2027 Sails: Nov 6, More...14 Night - Classic California Coast & Mexican Riviera
Starting in San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Nov 13, More...7 Night - Classic California Coast
Starting in San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California
2027 Sails: Nov 13, More...30 Night - Circle Hawaii & Sea of Cortez
Starting in San Diego, California, Hilo, Hawaii, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2027 Sails: Nov 18, More...
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
7 Night - Mexican RivieraStarting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 7, More...
15 Night - Panama Canal Eastward CruiseStarting in San Diego, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, George Town, Grand Cayman, Tampa, Florida
2027 Sails: Oct 7, More...
36 Night - Inca Coast Discovery Collectors' VoyageStarting in San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile, Puerto Montt, Chile, Puerto Chacabuco, Chile, Cruising Chilean Fjords, Pio XI Glacier (Bruggen Glacier), Chile, Scenic cruising Sarmiento Channel, Strait of Magellan, Punta Arenas, Chile, Cockburn Channel, Beagle Channel, Daylight cruising Glacier Alley, Ushuaia, Argentina, Scenic Cruising Cape Horn, Port Stanley, Falkland Islands, Montevideo, Uruguay, Buenos Aires, Argentina
2027 Sails: Oct 12, More...
21 Night - Inca Coast Discovery SegmentStarting in San Diego, California, Cabo San Lucas, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Crossing the Equator, Manta, Ecuador, Salaverry (Trujillo), Peru, Callao (Lima), Peru, General San Martin (Pisco), Peru, Arica, Chile, Coquimbo (La Serena), Chile, San Antonio CL (Santiago), Chile
2027 Sails: Oct 12, More...
35 Night - Hawaii, Tahiti & Marquesas Legendary VoyageStarting in San Diego, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Maui, Kona, Hawaii, Cross International Dateline, Tabuaeran (Fanning Island), Kiribati, Crossing the Equator, Cross International Dateline, Avatoru, Rangiroa, French Polynesia, Huahine, French Polynesia, Bora Bora, French Polynesia, Raiatea, Society Islands, French Polynesia, Bahia d Opunoha, Moorea, French Polynesia, Papeete, French Polynesia, Fakarava, Tuamotu, French Polynesia, Taiohae, Nuku Hiva, French Polynesia, Crossing the Equator, San Diego, California
2027 Sails: Oct 14, More...
7 Night - Baja PeninsulaStarting in San Diego, California, Loreto, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Oct 23, More...
14 Night - Baja Peninsula & Classic California CoastStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California
2027 Sails: Nov 6, More...
14 Night - Classic California Coast & Mexican RivieraStarting in San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Nov 13, More...
7 Night - Classic California CoastStarting in San Diego, California, Ensenada, Mexico, San Francisco, California, Santa Barbara, California, San Diego, California
2027 Sails: Nov 13, More...
30 Night - Circle Hawaii & Sea of CortezStarting in San Diego, California, Hilo, Hawaii, Kona, Hawaii, Kahului, Maui, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Ensenada, Mexico, San Diego, California, Cabo San Lucas, Mexico, Loreto, Mexico, Guaymas, Mexico, Topolobampo, Mexico, Pichilingue (La Paz), Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2027 Sails: Nov 18, More...
