Panama Cruise Departures
Cruises that depart from Central America: Panama
Cruises that visit Panama
Related areas: Balboa : Colon : Fuerte Amador : Panama City
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama
2027 Sails: Feb 13, More...
14 Night - Star Collector : Windward Islands & Spanish New World
Starting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad, Willemstad AN, Kralendijk, St Georges, Rodney Bay, The Pitons, Mayreau, Bequia, Bridgetown
2027 Sails: Feb 16, More...6 Night - Panama Canal, Cartagena, San Blas Islands & More
Starting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad
2027 Sails: Feb 16, More...
11 Night - Crescent Beaches & Colorful Towns
Starting in Panama City, Panama Canal Transit, Puerto Limon, Cruising the Caribbean Sea, Roatan, Harvest Caye, Santo Tomas De Castilla, Cozumel, Mexico, George Town, Montego Bay, Cruising the Straits of Florida, Miami
2027 Sails: Feb 22, More...
7 Night - Central America Jewels & Panama Canal
Starting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...
22 Night - Journey to the Amazon
Starting in Panama City, Panama Canal Transit, Cruising the Caribbean Sea, Oranjestad, Cruising the Caribbean Sea, Port of Spain, Cruising the Atlantic Ocean, Cruising the Amazon River, Manaus (Amazon River), Boca Da Valeria (Amazon River), Alter Do Chao (Amazon River), Cruising the Amazon River, Cruising the Atlantic Ocean, St Georges, Cruising the Caribbean Sea, Willemstad AN, Cruising the Caribbean Sea, Panama Canal Transit, Panama City
2027 Sails: Mar 9, More...10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...
10 Night - Panama & Pristine Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 15, More...
7 Night - Panama City / San Juan
Starting in Panama City, Transit Panama Canal, Guna Yala, San Blas Islands, Cartagena ES, Casa de Campo, San Juan
2027 Sails: Mar 28, More...
Cruises that depart from Central America: Panama
Cruises that visit Panama
Click on a cruise ship itinerary sailing from Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Balboa : Colon : Fuerte Amador : Panama City
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Colon, Panama
2027 Sails: Feb 13, More...
14 Night - Star Collector : Windward Islands & Spanish New WorldStarting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad, Willemstad AN, Kralendijk, St Georges, Rodney Bay, The Pitons, Mayreau, Bequia, Bridgetown
2027 Sails: Feb 16, More...
6 Night - Panama Canal, Cartagena, San Blas Islands & MoreStarting in Balboa / Fuerte Amador, Panama Canal, Bocas del Toro, San Blas, Panama, Cartagena CO, Oranjestad
2027 Sails: Feb 16, More...
11 Night - Crescent Beaches & Colorful TownsStarting in Panama City, Panama Canal Transit, Puerto Limon, Cruising the Caribbean Sea, Roatan, Harvest Caye, Santo Tomas De Castilla, Cozumel, Mexico, George Town, Montego Bay, Cruising the Straits of Florida, Miami
2027 Sails: Feb 22, More...
7 Night - Central America Jewels & Panama CanalStarting in Colon, San Blas Islands, Crossing the Panama Canal, Fuerte Amador, Flamenco Island, Playa Muerto, Darien National Park, Golfito, Puntarenas
2027 Sails: Feb 26, More...
22 Night - Journey to the AmazonStarting in Panama City, Panama Canal Transit, Cruising the Caribbean Sea, Oranjestad, Cruising the Caribbean Sea, Port of Spain, Cruising the Atlantic Ocean, Cruising the Amazon River, Manaus (Amazon River), Boca Da Valeria (Amazon River), Alter Do Chao (Amazon River), Cruising the Amazon River, Cruising the Atlantic Ocean, St Georges, Cruising the Caribbean Sea, Willemstad AN, Cruising the Caribbean Sea, Panama Canal Transit, Panama City
2027 Sails: Mar 9, More...
10 Night - Panama, Colombia & Caribbean IslandsStarting in Colon, San Blas Islands, Cartagena CO, Santa Marta, Bonaire, Tobago Cays, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Mar 12, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Colon, Panama
2027 Sails: Mar 13, Mar 27, More...
10 Night - Panama & Pristine IslesStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Santa Marta, Oranjestad, Willemstad AN, Port Antonio, Great Stirrup Cay, Miami
2027 Sails: Mar 15, More...
7 Night - Panama City / San JuanStarting in Panama City, Transit Panama Canal, Guna Yala, San Blas Islands, Cartagena ES, Casa de Campo, San Juan
2027 Sails: Mar 28, More...
