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Panama City Cruise Departures

Cruises that depart from Central America: Panama: Panama City

Cruises that visit Panama City

Click on a cruise ship itinerary sailing from Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.





Safari Voyager Cruises7 Night - Unveiled WondersŚCosta Rica & Panama Canal from Panama City to San Jose
Starting in San Jose; with stops in Granito de Oro; Coiba National Park; Golfo Dulce; Osa Conservation Area; Curu National Wildlife Refuge; San Jose
2020 Sails: Apr 27, May 11, 2021: Apr 17, May 1, More...
Safari Voyager Cruises7 Night - Colombia & PanamaŚCoral, Jungles, Canal from Panama City to Cartagena
Starting in Panama City; with stops in Darien Jungle; Isla Taboga; Panama Canal; Guna Yala; Capurgana; Sapzurro; Cartagena
2020 Sails: Oct 3, Oct 17, More...
Safari Voyager Cruises10 Night - Costa Rica & PanamaŚCanal, Culture, Adventure from Panama City to San Jose
Starting in Panama City; with stops in Fort San Lorenzo; Panama Canal; Darien Jungle; Pearl Islands Archipelago; Gulf of Panama; Granito de Oro; Coiba National Park; Golfo Dulce; Osa Conservation Area; Curo National Wildlife Refuge; San Jose
2020 Sails: Dec 18, 2021: Jan 7, Jan 27, Feb 16, Mar 8, Mar 28, More...
Oceania Sirena Cruises10 Night - Panama Potpourri - Panama City Panama to Miami Florida
Starting in Panama City with stops in Panama Canal Daylight Transit, Puerto Limon, Cruising the Caribbean Sea, Roatan, Santo Tomas, Harvest Caye, Costa Maya, Cruising the Straits of Florida, Key West, Miami
2022 Sails: Feb 1, More...
Crystal Endeavor Cruises10 Night - YEN221009-10 - Expedition: Darien Jungle to Colonial Lima
Starting in Panama City with stops in Pearl Island, Darien Jungle, Ensenada de Utrşa, Gorgona Island, Isla de la Plata, Lobos de Tierra, Salaverry, Isla Guanape, Callao
2022 Sails: Oct 9, More...

Panama City Cruise Departures

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