Panama Cruise Departures
Cruises that depart from Central America: Panama
Cruises that visit Panama
Related areas: Balboa : Colon : Fuerte Amador : Panama City
13 Night - Ancient Kingdoms and Natural Treasures : Panama to Chile
Starting in Panama City, Panama, Darien National Park / Playa del Muerto, Panama, Utria National Park / Ensenada de Utria, Colombia, Manta, Ecuador, Salaverry, Peru, Paracas, Peru, Pinguino de Humboldt National Reserve, Valparaiso, Chile
2027 Sails: Oct 31, More...
10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
10 Night - Classic Panama Canal Passage
Starting in Panama City (Fuerte Amador), Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Merida (Progreso), Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Nov 29, 2028: Nov 4, Dec 8, Dec 28, More...
10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 2, More...
7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), El Establo Mountain Hotel or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
11 Night - The Americas & Caribbean
Starting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...7 Night - Southern Caribbean Cruise
Starting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2027 Sails: Dec 18, 2028: Jan 15, Feb 19, Apr 15, More...10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 25, More...
Cruises that depart from Central America: Panama
Cruises that visit Panama
Click on a cruise ship itinerary sailing from Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Balboa : Colon : Fuerte Amador : Panama City
13 Night - Ancient Kingdoms and Natural Treasures : Panama to ChileStarting in Panama City, Panama, Darien National Park / Playa del Muerto, Panama, Utria National Park / Ensenada de Utria, Colombia, Manta, Ecuador, Salaverry, Peru, Paracas, Peru, Pinguino de Humboldt National Reserve, Valparaiso, Chile
2027 Sails: Oct 31, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Nov 28, More...
10 Night - Classic Panama Canal PassageStarting in Panama City (Fuerte Amador), Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Merida (Progreso), Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Nov 29, 2028: Nov 4, Dec 8, Dec 28, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 2, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama
2027 Sails: Dec 4, Dec 11, Dec 25, 2028: Jan 29, Feb 5, Feb 12, Mar 11, Mar 25, Apr 22, More...
7 Night - Costa Rica & Panama CanalStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise TourStarting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose, Santa Elena (Monteverde), El Establo Mountain Hotel or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, La Fortuna (Arenal), Tabacon Thermal Resort and Spa or Similar, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
11 Night - The Americas & CaribbeanStarting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...
7 Night - Southern Caribbean CruiseStarting in Colon, Panama, Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama
2027 Sails: Dec 18, 2028: Jan 15, Feb 19, Apr 15, More...
10 Night - Secrets of Central AmericaStarting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 25, More...
