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Panama Cruise Departures

Cruises that depart from Central America: Panama

Cruises that visit Panama

Click on a cruise ship itinerary sailing from Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Balboa : Colon : Flamenco Marina : Fuerte Amador : Panama City

S/C Panorama Cruise Ship7 Night - Treasures of Costa Rica & the Panama : Panama to Costa Rica - Panorama
Starting in Flamenco Marina with stops in Playa Muerto, Granito de Oro, Golfito, Drake Bay, Playa Biesanz, Puerto Caldera
2021 Sails: Jan 30, More...
Star Legend Cruise Tours11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour - Colon to San Jose
Cruise Ports: Departing from Colon, Panama with stops in; Panama Canal, Panama; Balboa / Fuerte Amador, Panama; Isla Parida, Panama; Puerto Jimenez (Gulfo Dulce), Costa Rica; Quepos, Cost Rica; Puerto Caldera, Costa Rica; Land Tour: Monteverde; Arenal; San Jose, Costa Rica
2021 Sails: Jan 30, Feb 13, Feb 27, Mar 13, More...
Wind Star Cruise Ship7 Night - Colon to Puerto Caldera-Wind Star-
Starting in Colon with stops in Panama Canal, Balboa / Fuerte Amador, Isla Parida, Puerto Jimenez, Quepos, Puerto Caldera
2021 Sails: Feb 6, More...
Wind Star Cruise Ship8 Night - Colon to Nassau-Wind Star-
Starting in Colon with stops in Cartagena, Nassau
2021 Sails: Feb 20, More...
Le Dumont-D'Urville Cruises9 Night - Island Gems and Underwater Treasures for the Caribbean from Colon to Fort-de-France
Starting in Colon, with stops in San Blas Islands, Cartagena, St George's, Mayreau, Soufriere , Fort de France
2021 Sails: Mar 1, More...
NCL Norwegian Sun Cruise Ship16 Night - Panama Canal from Panama City to Seattle: Cabo & Puerto Vallarta
Starting in Colon with stops in Puerto Limon, Daylight Transit Panama Canal, Puntarenas, San Juan del Sur, Acajutla, Puerto Quetzal, Huatulco, Puerto Vallarta, Cabo San Lucas, Seattle
2021 Sails: Mar 25, More...
Le Boreal Cruise Ship11 Night - Treasures of the Caribbean Sea from Colón to Miami
Starting in Colón; with stops in Puerto Cortes; Santo Tomas de Castilla; Half Moon Caye; Progresso; Miami
2021 Sails: Apr 9, More...
Safari Voyager Cruises7 Night - Unveiled Wonders—Costa Rica & Panama Canal from Panama City to San Jose
Starting in San Jose; with stops in Granito de Oro; Coiba National Park; Golfo Dulce; Osa Conservation Area; Curu National Wildlife Refuge; San Jose
2021 Sails: Apr 17, May 1, More...
Star Breeze Cruises7 Night - Colon to Puerto Caldera-Star Breeze-
Starting in Colon with stops in Panama Canal, Balboa / Fuerte Amador, Isla Parida, Puerto Jimenez, Quepos, Puerto Caldera
2021 Sails: May 2, More...
NCL Norwegian Sky Cruise Ship9 Night - Panama Canal from Panama City to Colon: Curacao & Aruba
Starting in Panama City with stops in Daylight Transit Panama Canal, Puerto Limon, Oranjestad, Kralendijk, Santa Marta, Cartagena, Colon
2021 Sails: Nov 2, More...

Panama Cruise Departures

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