Louisiana Cruise Departures

Cruises that depart from North America: United States: Louisiana

Cruises that visit Louisiana

See all River Cruises that depart from Louisiana

Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: New Orleans

7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Jamaica, New Orleans, Louisiana
2026 Sails: Nov 7, Nov 14, Nov 21, Nov 28, Dec 12, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 17, More...

American Cruise Lines, American Symphony

7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...

Carnival Cruise Lines, Carnival Liberty

6 Night - Western Caribbean
Starting in New Orleans, La, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 15, Dec 13, 2027: Nov 14, More...

Norwegian Line Tours, Norwegian Breakaway Tours

9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 20, Nov 27, Dec 11, Dec 18, Dec 25, More...

Carnival Cruise Lines, Carnival Liberty

8 Night - Bahamas
Starting in New Orleans, La, Celebration Key, the Bahamas, Relaxaway, Half Moon Cay, Nassau, Bahamas, New Orleans, La
2026 Sails: Nov 21, More...

Norwegian Cruise Line, Norwegian Breakaway

7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 22, Nov 29, Dec 13, Dec 20, Dec 27, 2027: Jan 3, Jan 10, Jan 17, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, More...

Carnival Cruise Lines, Carnival Liberty

14 Night - Journeys - Caribbean & Panama
Starting in New Orleans, La, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 29, 2027: Nov 28, More...

Norwegian Line Tours, Norwegian Breakaway Tours

9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, New Orleans, La
2026 Sails: Dec 4, More...

Royal Caribbean, Mariner of the Seas

7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Ocho Rios, Jamaica, New Orleans, Louisiana
2026 Sails: Dec 5, More...

Norwegian Cruise Line, Norwegian Breakaway

7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, New Orleans, La
2026 Sails: Dec 6, More...

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Louisiana Cruise Departures