Louisiana Cruise Departures
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Related areas: New Orleans
7 Night - Historic Mississippi River Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 9, 2027: Oct 28, Nov 3, Dec 21, Dec 27, 2028: Oct 27, Nov 2, More...
10 Night - New Orleans to Memphis
Starting in New Orleans, Louisiana, Darrow, Louisiana, Baton Rouge, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Oct 17, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Oct 7, More...
6 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2026 Sails: Nov 1, More...7 Night - Western Caribbean Cruise
Starting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Jamaica, New Orleans, Louisiana
2026 Sails: Nov 7, Nov 14, Nov 21, Nov 28, Dec 12, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 17, More...
6 Night - Western Caribbean
Starting in New Orleans, La, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 15, Dec 13, 2027: Nov 14, Dec 12, More...
9 Night - Historic New Orleans Pre Cruisetour
Starting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 20, Nov 27, Dec 11, Dec 18, Dec 25, More...8 Night - Bahamas
Starting in New Orleans, La, Celebration Key, the Bahamas, Relaxaway, Half Moon Cay, Nassau, Bahamas, New Orleans, La
2026 Sails: Nov 21, More...7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 22, Nov 29, Dec 13, Dec 20, Dec 27, 2027: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, More...14 Night - Journeys - Caribbean & Panama
Starting in New Orleans, La, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 29, 2027: Nov 28, More...
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: New Orleans
7 Night - Historic Mississippi River CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Oct 9, 2027: Oct 28, Nov 3, Dec 21, Dec 27, 2028: Oct 27, Nov 2, More...
10 Night - New Orleans to MemphisStarting in New Orleans, Louisiana, Darrow, Louisiana, Baton Rouge, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: Oct 17, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA / Houmas House, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Oct 29, 2027: Oct 8, 2028: Oct 7, More...
6 Night - Western Caribbean CruiseStarting in New Orleans, Louisiana, Puerto Costa Maya, Mexico, Belize City, Belize, Cozumel, Mexico, New Orleans, Louisiana
2026 Sails: Nov 1, More...
7 Night - Western Caribbean CruiseStarting in New Orleans, Louisiana, Cozumel, Mexico, George Town, Grand Cayman, Falmouth, Jamaica, New Orleans, Louisiana
2026 Sails: Nov 7, Nov 14, Nov 21, Nov 28, Dec 12, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 17, More...
6 Night - Western CaribbeanStarting in New Orleans, La, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 15, Dec 13, 2027: Nov 14, Dec 12, More...
9 Night - Historic New Orleans Pre CruisetourStarting in At Hotel, New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 20, Nov 27, Dec 11, Dec 18, Dec 25, More...
8 Night - BahamasStarting in New Orleans, La, Celebration Key, the Bahamas, Relaxaway, Half Moon Cay, Nassau, Bahamas, New Orleans, La
2026 Sails: Nov 21, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Nov 22, Nov 29, Dec 13, Dec 20, Dec 27, 2027: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, More...
14 Night - Journeys - Caribbean & PanamaStarting in New Orleans, La, Montego Bay, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, New Orleans, La
2026 Sails: Nov 29, 2027: Nov 28, More...
