Louisiana Cruise Departures
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Related areas: New Orleans
14 Night - Bayous, Blues & Bluegrass
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 4, 2028: Jun 2, More...
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 11, 2028: Jun 9, More...
15 Night - Mississippi & Tennessee Rivers Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Savannah, TN, Florence, AL, Huntsville, AL
2027 Sails: Jun 26, 2028: Jun 25, More...7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2027 Sails: Jun 29, More...
13 Night - Mississippi & Ohio Rivers Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, Day of River Cruising, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2027 Sails: Jul 6, 2028: Jul 2, More...21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton), Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2027 Sails: Jul 6, More...14 Night - The Big Easy to the Gateway City
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton)
2027 Sails: Jul 6, More...
15 Night - Mississippi & Cumberland Rivers Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, Day of River Cruising, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Dover TN, Clarksville, TN, Nashville, TN
2027 Sails: Jul 13, 2028: Jul 11, More...21 Night - Mississippi River Odyssey
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton), Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2027 Sails: Aug 10, 2028: Aug 15, More...
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: New Orleans
14 Night - Bayous, Blues & BluegrassStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Lower Mississippi, Paducah, Kentucky, Henderson, Kentucky, Owensboro, Kentucky, Louisville, Kentucky
2027 Sails: Jun 1, Oct 26, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 4, 2028: Jun 2, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2027 Sails: Jun 11, 2028: Jun 9, More...
15 Night - Mississippi & Tennessee Rivers CruiseStarting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Savannah, TN, Florence, AL, Huntsville, AL
2027 Sails: Jun 26, 2028: Jun 25, More...
7 Night - New Orleans & Southern CharmsStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2027 Sails: Jun 29, More...
13 Night - Mississippi & Ohio Rivers CruiseStarting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, Day of River Cruising, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2027 Sails: Jul 6, 2028: Jul 2, More...
21 Night - Mississippi River OdysseyStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton), Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2027 Sails: Jul 6, More...
14 Night - The Big Easy to the Gateway CityStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton)
2027 Sails: Jul 6, More...
15 Night - Mississippi & Cumberland Rivers CruiseStarting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Baton Rouge, LA, Day of River Cruising, Natchez, MS, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of Cruising, Paducah, KY, Day of River Cruising, Dover TN, Clarksville, TN, Nashville, TN
2027 Sails: Jul 13, 2028: Jul 11, More...
21 Night - Mississippi River OdysseyStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, St Louis, Missouri (Alton), Hannibal, Missouri, Burlington, Iowa, Quad Cities, Iowa, Dubuque, Iowa, La Crosse, Wisconsin, Red Wing, Minnesota, St Paul, Minnesota
2027 Sails: Aug 10, 2028: Aug 15, More...
