Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Olbia : Palermo : Perugia : Ravenna : Rome : Savona : Taormina : Taranto : Trieste : Venice

Costa Cruise Lines, Costa Fascinosa

7 Night - Eastern Mediterranean from Catania
Starting in Catania, Taranto, Argostoli (Cephalonia), Mykonos, Piraeus (Athens), Malta / La Valletta, Catania
2026 Sails: Jul 11, Jul 25, Aug 22, Sep 5, More...

Costa Cruise Lines, Costa Smeralda

7 Night - Western Mediterranean from Savona
Starting in Savona, Marseille, Barcelona, Ibiza, Palermo, Civitavecchia (Rome), Savona
2026 Sails: Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, Aug 29, Sep 5, Sep 12, Sep 19, More...

Emerald Cruises, Emerald Kaia

7 Night - Croatian Coast and the Best of the Adriatic
Starting in Venice, Italy, Rovinj, Croatia, Sibenik, Croatia, Trogir, Croatia, Vis / Hvar, Croatia, Hvar, Croatia, Korcula, Croatia, Dubrovnik, Croatia
2026 Sails: Jul 11, Aug 1, Aug 15, More...

Royal Caribbean, Explorer of the Seas

7 Night - Greek Isles Cruise
Starting in Ravenna, Italy, Santorini, Greece, Athens (Piraeus), Greece, Mykonos, Greece, Split, Croatia, Ravenna, Italy
2026 Sails: Jul 11, Oct 3, More...

Royal Caribbean, Legend of the Seas

7 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 11, More...

Costa Cruise Lines, Costa Fascinosa

7 Night - Eastern Mediterranean from Taranto
Starting in Taranto, Argostoli (Cephalonia), Mykonos, Piraeus (Athens), Malta / La Valletta, Catania, Taranto
2026 Sails: Jul 12, Jul 26, Aug 23, Sep 6, More...

MSC Cruises, MSC Musica

7 Night - Mediterranean
Starting in Cagliari (Sardinia), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Valencia, Spain, Ibiza (Balearic Islands), Spain, Cagliari (Sardinia), Italy
2026 Sails: Jul 12, Jul 19, Jul 26, Aug 9, Aug 16, Aug 23, Aug 30, More...

MSC Cruises, MSC World Europa

7 Night - Mediterranean
Starting in Genoa (Portofino), Italy, Naples (Pompeii), Italy, Messina (Taormina), Italy, La Valletta, Malta, Barcelona, Spain, Marseille (Provence), France, Genoa (Portofino), Italy
2026 Sails: Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 20, Sep 27, Oct 4, Oct 11, Oct 18, Oct 25, Nov 1, More...

Norwegian Cruise Line, Norwegian Gem

7 Night - Eastern Mediterranean
Starting in Civitavecchia Rome, Italy, Amalfi Coast (Salerno), Italy, Catania, Italy, Corfu, Greece, Kotor, Montenegro, Split, Croatia, Venice (Trieste), Italy, Venice (Ravenna), Italy
2026 Sails: Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, More...

Norwegian Cruise Line, Norwegian Pearl

7 Night - Europe - Greek Isles - Venice
Starting in Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Corfu, Greece, Olympia / Katakolon, Greece, Mykonos, Greece, Santorini Island, Greece, Piraeus / Athens, Greece
2026 Sails: Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, More...

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