Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Royal Caribbean, Explorer of the Seas

7 Night - Greek Isles Cruise
Starting in Ravenna, Italy, Santorini, Greece, Athens (Piraeus), Greece, Mykonos, Greece, Split, Croatia, Ravenna, Italy
2026 Sails: Jul 11, Oct 3, More...

Royal Caribbean, Legend of the Seas

7 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 11, More...

Seabourn, Seabourn Quest

7 Night - Adriatic & Grecian Gems
Starting in Fusina (Venice), Italy, Vodice (Sibenik), Croatia, Kotor, Montenegro, Scenic cruising Bay of Kotor, Corfu, Greece, Sami, Cephalonia, Greece, Nafplion, Greece, Piraeus (Athens), Greece
2026 Sails: Jul 12, Sep 6, More...

Seabourn, Seabourn Quest

14 Night - Ephesus, Grecian Gems & Adriatic
Starting in Fusina (Venice), Italy, Vodice (Sibenik), Croatia, Kotor, Montenegro, Scenic cruising Bay of Kotor, Corfu, Greece, Sami, Cephalonia, Greece, Nafplion, Greece, Piraeus (Athens), Greece, Mykonos, Greece, Agios Nikolaos, Crete, Greece, Kusadasi (Ephesus), Turkey, Kos, Greece, Symi, Greece, Piraeus (Athens), Greece
2026 Sails: Jul 12, More...

Seabourn, Seabourn Quest

21 Night - Ephesus, Adriatic, Grecian Gems & Dalmatian Coast
Starting in Fusina (Venice), Italy, Vodice (Sibenik), Croatia, Kotor, Montenegro, Scenic cruising Bay of Kotor, Corfu, Greece, Sami, Cephalonia, Greece, Nafplion, Greece, Piraeus (Athens), Greece, Mykonos, Greece, Agios Nikolaos, Crete, Greece, Kusadasi (Ephesus), Turkey, Kos, Greece, Symi, Greece, Piraeus (Athens), Greece, Santorini, Greece, Monemvasia, Greece, Itea (Delphi), Greece, Nydri, Lefkada, Greece, Sarande, Albania, Dubrovnik, Croatia
2026 Sails: Jul 12, More...

Silversea, Silver Muse

9 Night - Fusina to Fusina
Starting in Fusina (Venice), Koper, Rovinj, Kotor, Bari, Dubrovnik, Croatia, Split, Zadar, Fusina (Venice)
2026 Sails: Jul 12, More...

Silversea, Silver Ray

7 Night - Civitavecchia to Monte Carlo
Starting in Civitavecchia (Rome), Sorrento, Porto Santo Stefano, Livorno (Tuscany), Portofino, Toulon, Monte Carlo
2026 Sails: Jul 12, More...

Silversea, Silver Ray

13 Night - Europe from Rome (Civitavecchia) to Barcelona
Starting in Civitavecchia, Sorrento, Porto Santo Stefano, Livorno, Portofino, Toulon, Monte Carlo, Saint Tropez, Cartagena ES, Valencia, Palma De Mallorca, Barcelona
2026 Sails: Jul 12, More...

Cunard Line, Queen Victoria

7 Night - France and Italy
Starting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy
2026 Sails: Jul 13, More...

Cunard Line, Queen Victoria

14 Night - Italy, France and Spain
Starting in Civitavecchia (tours to Rome), Italy, Marseille, France, Villefranche, France, Genoa, Italy, La Spezia (tours to Florence or Pisa), Italy, Civitavecchia (tours to Rome), Italy, Livorno (tours to Florence or Pisa), Italy, La Seyne-sur-Mer (for Toulon), France, Calvi, Corsica, France, Valencia, Spain, Barcelona, Spain
2026 Sails: Jul 13, More...

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